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Fmc1 Gene Detail
Summary
  • Symbol
    Fmc1
  • Name
    formation of mitochondrial complex V assembly factor 1
  • Synonyms
    1110001J03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913367
    NCBI Gene: 66117
Location & Maps
more
  • Sequence Map
    Chr6:38533502-38539449 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5948 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 17.84 cM, cytoband B1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    FMC1, formation of mitochondrial complex V assembly factor 1 homolog
  • Vertebrate Orthologs
    9
  • Human Ortholog
    FMC1, formation of mitochondrial complex V assembly factor 1 homolog
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C7orf55, HSPC268
  • Links
    NCBI Gene ID: 154791
    neXtProt AC: NX_Q96HJ9

  • Chr Location
    7q34; chr7:139340450-139346319 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 41627
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: FMC1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    80
  • Gene trapped
    76
  • Targeted
    4
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024224 VEGA Gene Model | MGI Sequence Detail 5948 C57BL/6J ±  kb
transcript OTTMUST00000059279 VEGA | MGI Sequence Detail 479 Not Applicable  
polypeptide OTTMUSP00000028825 VEGA | MGI Sequence Detail 113 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    38 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:228369 Higashi S, et al., p13 overexpression in pancreatic beta-cells ameliorates type 2 diabetes in high-fat-fed mice. Biochem Biophys Res Commun. 2015 Jun 12;461(4):612-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory