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Apoa5
Gene Detail
 Symbol
Name
ID
Apoa5
apolipoprotein A-V
MGI:1913363
Synonyms 1300007O05Rik, Apoav, RAP3
Feature Type protein coding gene
Genetic Map
Chromosome 9
25.37 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr9:46268633-46271919 bp, + strand
From VEGA annotation of GRCm38

  3287 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:14197  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Apoa5

Human
homologs
Human Homolog APOA5, apolipoprotein A-V
NCBI Gene ID 116519
neXtProt AC  NX_Q6Q788
Human Synonyms  APOAV, RAP3
Human Chr (Location)  11q23; chr11:116789367-116792420 (-)  GRCh38
Disease Associations  (2) Diseases Associated with Human APOA5
Alleles
and
phenotypes
All alleles(5) : Targeted(5)
 
Homozygous mutation of this gene results in increased triglyceride and VLDL cholesterol levels.
 
Gene Ontology
(GO)
classifications
All GO classifications: (35 annotations)
Process acylglycerol homeostasis, cholesterol homeostasis, ...
Component chylomicron, extracellular region, ...
Function enzyme activator activity, enzyme binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (1)    Tissues (1)    Images (1)
Theiler Stages: 23
Assay TypeResults
RNA in situ 1
cDNA source data(184)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(184) cDNA(184)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000028704 (Evidence)
Ensembl Gene ModelENSMUSG00000032079 (Evidence)
Entrez Gene66113 (Evidence)
UniGene29738
DFCITC1575460
DoTSDT.536273, DT.94366441, DT.99842157
NIA Mouse Gene IndexU010436
Consensus CDS ProjectCCDS23143.1
International Mouse Knockout Project StatusApoa5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028704 VEGA Gene Model | MGI Sequence Detail 3287 C57BL/6J ±  kb
transcript OTTMUST00000071088 VEGA | MGI Sequence Detail 2515 Not Applicable 
polypeptide OTTMUSP00000036352 VEGA | MGI Sequence Detail 368 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(58 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000074 Apolipoprotein A1/A4/E
Protein Ontology PR:000004144 apolipoprotein A-V
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:203562 van den Berg SA, et al., Apolipoprotein A5 deficiency aggravates high-fat diet-induced obesity due to impaired central regulation of food intake. FASEB J. 2013 Aug;27(8):3354-62
All references(47)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory