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Marc1 Gene Detail
Summary
  • Symbol
    Marc1
  • Name
    mitochondrial amidoxime reducing component 1
  • Synonyms
    1300013F15Rik, Mosc1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913362
    NCBI Gene: 66112
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:184786767-184811308 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 89.07 cM, cytoband H4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    325 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913362
protein coding gene Chr1:184786767-184811313 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016909
protein coding gene Chr1:191478698-191504455 (-)
A/J MGP_AJ_G0016888
protein coding gene Chr1:183665828-183689489 (-)
AKR/J MGP_AKRJ_G0016853
protein coding gene Chr1:189080794-189106039 (-)
BALB/cJ MGP_BALBcJ_G0016846
protein coding gene Chr1:184302697-184326519 (-)
C3H/HeJ MGP_C3HHeJ_G0016670
protein coding gene Chr1:189919512-189943993 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017309
protein coding gene Chr1:197597298-197624718 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015016
protein coding gene Chr1:174659492-174684608 (-)
CAST/EiJ MGP_CASTEiJ_G0016253
protein coding gene Chr1:189340626-189368110 (-)
CBA/J MGP_CBAJ_G0016644
protein coding gene Chr1:204967549-204991792 (-)
DBA/2J MGP_DBA2J_G0016750
protein coding gene Chr1:182427979-182451431 (-)
FVB/NJ MGP_FVBNJ_G0016746
protein coding gene Chr1:180525454-180549349 (-)
LP/J MGP_LPJ_G0016825
protein coding gene Chr1:192634773-192663303 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016778
protein coding gene Chr1:211877706-211902087 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017346
protein coding gene Chr1:188931748-188955873 (-)
PWK/PhJ MGP_PWKPhJ_G0016040
protein coding gene Chr1:181622831-181647700 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015816
protein coding gene Chr1:187896809-187922944 (-)
WSB/EiJ MGP_WSBEiJ_G0016315
protein coding gene Chr1:189108138-189133601 (-)



Homology
more
  • Human Ortholog
    MARC1, mitochondrial amidoxime reducing component 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MARC1, mitochondrial amidoxime reducing component 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MOSC1
  • Links
    NCBI Gene ID: 64757
    neXtProt AC: NX_Q5VT66
    UniProt: Q5VT66

  • Chr Location
    1q41; chr1:220786697-220814399 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 129604
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MARC1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66112 NCBI Gene Model | MGI Sequence Detail 24542 C57BL/6J ±  kb
transcript NM_001290273 RefSeq | MGI Sequence Detail 2148 C57BL/6  
polypeptide Q9CW42 UniProt | EBI | MGI Sequence Detail 340 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • EC
  • InterPro Domains
    IPR005302 Molybdenum cofactor sulfurase, C-terminal
    IPR005303 MOSC, N-terminal beta barrel
    IPR011037 Pyruvate kinase-like, insert domain superfamily
Molecular
Reagents
less
  • All nucleic 37
    cDNA 37

    Microarray probesets 4
References
more
  • Summaries
    All 24
    Gene Ontology 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:221087 Jakobs HH, et al., The N-reductive system composed of mitochondrial amidoxime reducing component (mARC), cytochrome b5 (CYB5B) and cytochrome b5 reductase (CYB5R) is regulated by fasting and high fat diet in mice. PLoS One. 2014;9(8):e105371

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory