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Ndufa9 Gene Detail
Summary
  • Symbol
    Ndufa9
  • Name
    NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9
  • Synonyms
    1010001N11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913358
    NCBI Gene: 66108
  • Gene Overview
    MyGene.info: NDUFA9
Location & Maps
more
  • Sequence Map
    Chr6:126821721-126849136 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      27416 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    NDUFA9, NADH:ubiquinone oxidoreductase subunit A9
  • Vertebrate Orthologs
    11
  • Human Ortholog
    NDUFA9, NADH:ubiquinone oxidoreductase subunit A9
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CC6, CI39k, CI-39k, NDUFS2L, SDR22E1
  • Links
    NCBI Gene ID: 4704
    neXtProt AC: NX_Q16795

  • Chr Location
    12p13.3; chr12:4649098-4687554 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 3666
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;2 zebrafish
  • HCOP
    human homology predictions: NDUFA9
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human NDUFA9 associations

Human Disease Mouse Models
       Leigh Syndrome; LS   OMIM: 256000
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000056335 VEGA Gene Model | MGI Sequence Detail 27416 C57BL/6J ±  kb
transcript OTTMUST00000139223 VEGA | MGI Sequence Detail 1445 Not Applicable  
polypeptide OTTMUSP00000073078 VEGA | MGI Sequence Detail 377 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    164 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000011080 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial
  • InterPro Domains
    IPR016040 NAD(P)-binding domain
    IPR008030 NmrA-like domain
Molecular
Reagents
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  • All nucleic 202
    cDNA 201
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 39
    Developmental Gene Expression 7
    Gene Ontology 9
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:206222 Peralta S, et al., Partial complex I deficiency due to the CNS conditional ablation of Ndufa5 results in a mild chronic encephalopathy but no increase in oxidative damage. Hum Mol Genet. 2014 Mar 15;23(6):1399-412

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory