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Carkd Gene Detail
Summary
  • Symbol
    Carkd
  • Name
    carbohydrate kinase domain containing
  • Synonyms
    0710008K08Rik, 2810407E01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913353
    NCBI Gene: 69225
  • Gene Overview
    MyGene.info: NAXD
Location & Maps
more
  • Sequence Map
    Chr8:11497506-11514960 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      17455 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    NAXD, NAD(P)HX dehydratase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NAXD, NAD(P)HX dehydratase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CARKD, LP3298
  • Links
    NCBI Gene ID: 55739
    neXtProt AC: NX_Q8IW45

  • Chr Location
    13q34; chr13:110615460-110639996 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 6333
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: NAXD
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042282 VEGA Gene Model | MGI Sequence Detail 17455 C57BL/6J ±  kb
transcript OTTMUST00000111244 VEGA | MGI Sequence Detail 1359 Not Applicable  
polypeptide OTTMUSP00000062218 VEGA | MGI Sequence Detail 365 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    263 from dbSNP Build 142
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000029646 ATP-dependent (S)-NAD(P)H-hydrate dehydratase
  • EC
  • InterPro Domains
    IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase
    IPR029056 Ribokinase-like
Molecular
Reagents
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  • All nucleic 87
    cDNA 86
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1916475
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:212424 Marbaix AY, et al., Occurrence and subcellular distribution of the NADPHX repair system in mammals. Biochem J. 2014 May 15;460(1):49-58

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory