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Chchd6 Gene Detail
Summary
  • Symbol
    Chchd6
  • Name
    coiled-coil-helix-coiled-coil-helix domain containing 6
  • Synonyms
    0710001P09Rik, 1700021B03Rik, Micos25
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913348
    NCBI Gene: 66098
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:89383146-89595652 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 39.91 cM, cytoband D2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    534 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913348
protein coding gene Chr6:89383146-89595652 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031020
protein coding gene Chr6:90834068-91049127 (-)
A/J MGP_AJ_G0030986
protein coding gene Chr6:87378842-87590451 (-)
AKR/J MGP_AKRJ_G0030917
protein coding gene Chr6:89846944-90058519 (-)
BALB/cJ MGP_BALBcJ_G0030999
protein coding gene Chr6:87352184-87560711 (-)
C3H/HeJ MGP_C3HHeJ_G0030711
protein coding gene Chr6:94399778-94603156 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031456
protein coding gene Chr6:93275422-93489685 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028637
protein coding gene Chr6:85446602-85650201 (-)
CAST/EiJ MGP_CASTEiJ_G0030108
protein coding gene Chr6:89952614-90164419 (-)
CBA/J MGP_CBAJ_G0030683
protein coding gene Chr6:96777359-96990703 (-)
DBA/2J MGP_DBA2J_G0030839
protein coding gene Chr6:86616474-86821419 (-)
FVB/NJ MGP_FVBNJ_G0030792
protein coding gene Chr6:85818944-86024118 (-)
LP/J MGP_LPJ_G0030916
protein coding gene Chr6:90864753-91076068 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030825
protein coding gene Chr6:100917133-101127738 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031483
protein coding gene Chr6:89692157-89898483 (-)
PWK/PhJ MGP_PWKPhJ_G0029823
protein coding gene Chr6:85592672-85800988 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029651
protein coding gene Chr6:88527177-88757154 (-)
WSB/EiJ MGP_WSBEiJ_G0030189
protein coding gene Chr6:90140398-90353667 (-)



Homology
more
  • Human Ortholog
    CHCHD6, coiled-coil-helix-coiled-coil-helix domain containing 6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CHCHD6, coiled-coil-helix-coiled-coil-helix domain containing 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CHCM1, Mic25, MICOS25, PPP1R23
  • Links
    NCBI Gene ID: 84303
    neXtProt AC: NX_Q9BRQ6
    UniProt: Q9BRQ6

  • Chr Location
    3q21.3; chr3:126704220-126960420 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11920
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CHCHD6
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66098 NCBI Gene Model | MGI Sequence Detail 212507 C57BL/6J ±  kb
transcript NM_025351 RefSeq | MGI Sequence Detail 1126 C57BL/6  
polypeptide Q91VN4 UniProt | EBI | MGI Sequence Detail 273 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR007964 MICOS complex subunit MIC19/MIC25
Molecular
Reagents
less
  • All nucleic 61
    cDNA 61

    Microarray probesets 3
Other
Accession IDs
less
MGI:1916633
References
more
  • Summaries
    All 30
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory