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Lamtor4 Gene Detail
Summary
  • Symbol
    Lamtor4
  • Name
    late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
  • Synonyms
    0910001L09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913346
    NCBI Gene: 66096
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:138253744-138257657 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 77.00 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    177 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913346
 protein coding gene Chr5:138253744-138257660 (+)
129S1/SvImJ ENSMUSG00200042190
 protein coding gene Chr5:132125874-132129787 (+)
A/J ENSMUSG00195047679
 protein coding gene Chr5:131659186-131663099 (+)
AKR/J ENSMUSG00220046997
 protein coding gene Chr5:131004541-131008454 (+)
BALB/cJ ENSMUSG00180040302
 protein coding gene Chr5:131755782-131759696 (+)
C3H/HeJ ENSMUSG00175041493
 protein coding gene Chr5:133683242-133687155 (+)
C57BL/6NJ ENSMUSG00215047116
 protein coding gene Chr5:131697438-131701352 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027909
 protein coding gene Chr5:131003585-131007407 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210022583
 protein coding gene Chr5:132500759-132504672 (+)
DBA/2J ENSMUSG00185053814
 protein coding gene Chr5:135516117-135520030 (+)
FVB/NJ ENSMUSG00205046160
 protein coding gene Chr5:131317667-131321580 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230045206
 protein coding gene Chr5:139629568-139633481 (+)
NOD/ShiLtJ ENSMUSG00190044359
 protein coding gene Chr5:131455443-131459356 (+)
NZO/HlLtJ ENSMUSG00225020663
 protein coding gene Chr5:147183038-147187109 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    LAMTOR4, late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LAMTOR4, late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
  • Synonyms
    C7orf59
  • Links
    NCBI Gene ID: 389541
    UniProt: Q0VGL1

  • Chr Location
    7q22.1; chr7:100148912-100155944 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    611
  • Tissues
    8
  • cDNA Data
    67
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66096 NCBI Gene Model | MGI Sequence Detail 3914 C57BL/6J ±  kb
    transcript NM_001081108 RefSeq | MGI Sequence Detail 900 C57BL/6  
    polypeptide Q8CF66 UniProt | EBI | MGI Sequence Detail 99 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 68
      cDNA 68
      Antibodies 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2141100
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 2
      Gene Ontology 7
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory