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Lsm7 Gene Detail
Summary
  • Symbol
    Lsm7
  • Name
    LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
  • Synonyms
    0910001B06Rik, 1110033F18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913344
    NCBI Gene: 66094
  • Gene Overview
    MyGene.info: LSM7
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:80852821-80855209 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 39.72 cM, cytoband C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    18 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913344
protein coding gene Chr10:80852821-80855247 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017524
protein coding gene Chr10:81514991-81519330 (-)
A/J MGP_AJ_G0017502
protein coding gene Chr10:78645059-78647446 (-)
AKR/J MGP_AKRJ_G0017463
protein coding gene Chr10:80799901-80802658 (-)
BALB/cJ MGP_BALBcJ_G0017464
protein coding gene Chr10:78861036-78863421 (-)
C3H/HeJ MGP_C3HHeJ_G0017287
protein coding gene Chr10:80886419-80889789 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017918
protein coding gene Chr10:84310970-84315705 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015607
protein coding gene Chr10:74856396-74858836 (-)
CAST/EiJ MGP_CASTEiJ_G0016854
protein coding gene Chr10:81119782-81122297 (-)
CBA/J MGP_CBAJ_G0017259
protein coding gene Chr10:87587913-87590293 (-)
DBA/2J MGP_DBA2J_G0017365
protein coding gene Chr10:77843458-77845841 (-)
FVB/NJ MGP_FVBNJ_G0017359
protein coding gene Chr10:77074746-77078982 (-)
LP/J MGP_LPJ_G0017436
protein coding gene Chr10:81974358-81976738 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017385
protein coding gene Chr10:89499807-89502192 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017959
protein coding gene Chr10:80796023-80798408 (-)
PWK/PhJ MGP_PWKPhJ_G0016635
protein coding gene Chr10:77736414-77738815 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016425
protein coding gene Chr10:79745241-79747638 (-)
WSB/EiJ MGP_WSBEiJ_G0016914
protein coding gene Chr10:80831466-80834950 (-)



Homology
more
  • Human Ortholog
    LSM7, LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
  • Vertebrate Orthologs
    9
  • Human Ortholog
    LSM7, LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
    Orthology source: HomoloGene, HGNC
  • Synonyms
    YNL147W
  • Links
    NCBI Gene ID: 51690
    neXtProt AC: NX_Q9UK45
    UniProt: Q9UK45

  • Chr Location
    19p13.3; chr19:2321521-2328615 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035215 Ensembl Gene Model | MGI Sequence Detail 2389 C57BL/6J ±  kb
transcript ENSMUST00000035775 Ensembl | MGI Sequence Detail 468 Not Applicable  
polypeptide ENSMUSP00000044993 Ensembl | MGI Sequence Detail 103 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR001163 LSM domain, eukaryotic/archaea-type
    IPR010920 LSM domain superfamily
    IPR017132 Sm-like protein Lsm7
Molecular
Reagents
less
  • All nucleic 62
    cDNA 61
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1915966
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:216429 Perez-Santangelo S, et al., Role for LSM genes in the regulation of circadian rhythms. Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):15166-71

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory