About   Help   FAQ
Emc3 Gene Detail
Summary
  • Symbol
    Emc3
  • Name
    ER membrane protein complex subunit 3
  • Synonyms
    0610039A15Rik, Tmem111
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913337
    NCBI Gene: 66087
Location & Maps
more
  • Sequence Map
    Chr6:113514874-113531652 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      16779 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 52.78 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    EMC3, ER membrane protein complex subunit 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    EMC3, ER membrane protein complex subunit 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    POB, TMEM111
  • Links
    NCBI Gene ID: 55831
    neXtProt AC: NX_Q9P0I2

  • Chr Location
    3p25.3; chr3:9962682-10011116 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    10
  • Gene trapped
    5
  • Spontaneous
    1
  • Targeted
    4
  • Genomic Mutations
    1 involving Emc3
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023489 VEGA Gene Model | MGI Sequence Detail 16779 C57BL/6J ±  kb
transcript OTTMUST00000057169 VEGA | MGI Sequence Detail 1985 Not Applicable  
polypeptide OTTMUSP00000027555 VEGA | MGI Sequence Detail 261 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    59 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000029445 ER membrane protein complex subunit 3
  • InterPro Domains
    IPR002809 Protein of unknown function DUF106, transmembrane
    IPR008568 Uncharacterised conserved protein UCP010045, transmembrane eukaryotic
Molecular
Reagents
less
  • All nucleic 110
    cDNA 110

    Microarray probesets 4
Other
Accession IDs
less
MGI:1353660, MGI:2141673
References
more
  • Summaries
    All 35
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory