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Eif3f
Gene Detail
 Symbol
Name
ID
Eif3f
eukaryotic translation initiation factor 3, subunit F
MGI:1913335
Synonyms 0610037M02Rik, Eif3s5
Feature Type protein coding gene
Genetic Map
Chromosome 7
57.21 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:108934417-108942951 bp, + strand
From VEGA annotation of GRCm38

  8535 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2783  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: translation initiation factor 3 subunit 5, eukaryotic
Gene Tree: Eif3f

Human
homologs
Human Homolog EIF3F, eukaryotic translation initiation factor 3, subunit F
NCBI Gene ID 8665
neXtProt AC  NX_O00303
Human Synonyms  eIF3-p47, EIF3S5
Human Chr (Location)  11p15.4; chr11:7987320-7996171 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(2) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Eif3f interacts with 190 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process protein deubiquitination, proteolysis, ...
Component cytoplasm, eukaryotic translation initiation factor 3 complex, ...
Function cysteine-type peptidase activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (13)    Tissues (13)    Images (2)
Theiler Stages: 17, 23
Assay TypeResults
RNA in situ 13
cDNA source data(303)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(303) cDNA(303)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000026004 (Evidence)
Ensembl Gene ModelENSMUSG00000031029 (Evidence)
Entrez Gene66085 (Evidence)
UniGene182962
DFCITC1573232
DoTSDT.101236732, DT.101259778, DT.111018660, DT.111018691, DT.94354515, DT.97383376
NIA Mouse Gene IndexU008614
EC3.4.19.12
Consensus CDS ProjectCCDS21731.1
International Mouse Knockout Project StatusEif3f
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026004 VEGA Gene Model | MGI Sequence Detail 8535 C57BL/6J ±  kb
transcript OTTMUST00000064170 VEGA | MGI Sequence Detail 2514 Not Applicable 
polypeptide OTTMUSP00000031829 VEGA | MGI Sequence Detail 361 Not Applicable 

For the selected sequences
All sequences(63) RefSeq(2) UniProt(7)
Polymorphisms SNPs within 2kb(103 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027531 Eukaryotic translation initiation factor 3 subunit F
InterPro IPR000555 JAB1/Mov34/MPN/PAD-1
InterPro IPR024969 Rpn11/EIF3F C-terminal domain
Protein Ontology PR:000006978 eukaryotic translation initiation factor 3 subunit F
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:204915 Zeng L, et al., The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control. J Biol Chem. 2013 Oct 18;288(42):30087-93
All references(38)
Other
accession IDs
MGI:2141824

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory