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Sdhaf2
Gene Detail
 Symbol
Name
ID
Sdhaf2
succinate dehydrogenase complex assembly factor 2
MGI:1913322
Synonyms 0610038F07Rik
Feature Type protein coding gene
Genetic Map
Chromosome 19
6.60 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:10500513-10525209 bp, - strand
From Ensembl annotation of GRCm38

  24697 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32370  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Sdhaf2

Human
homologs
Human Homolog SDHAF2, succinate dehydrogenase complex assembly factor 2
NCBI Gene ID 54949
neXtProt AC  NX_Q9NX18
Human Synonyms  C11orf79, PGL2, SDH5
Human Chr (Location)  11q12.2; chr11:61430125-61446767 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human SDHAF2
Mutations,
alleles, and
phenotypes
All mutations/alleles(16) : Gene trapped(12) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Sdhaf2 interacts with 293 markers (Mir1b, Mir7-1, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process mitochondrial electron transport, succinate to ubiquinone, negative regulation of canonical Wnt signaling pathway, ...
Component mitochondrion
Function molecular_function
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000024668 (Evidence)
Entrez Gene66072 (Evidence)
DFCITC1576933, TC1589223, TC1603093, TC1612944, TC1631118, TC1636771, TC1653334
DoTSDT.101161470, DT.101240779, DT.101741169, DT.534714, DT.97391892, DT.99848720
NIA Mouse Gene IndexU038802
Consensus CDS ProjectCCDS29578.1
International Mouse Knockout Project StatusSdhaf2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024668 Ensembl Gene Model | MGI Sequence Detail 24697 C57BL/6J ±  kb
transcript ENSMUST00000025570 Ensembl | MGI Sequence Detail 3096 Not Applicable 
polypeptide ENSMUSP00000025570 Ensembl | MGI Sequence Detail 164 Not Applicable 

For the selected sequences
All sequences(47) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(178 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005631 Protein of unknown function DUF339
Protein Ontology PR:000031667 succinate dehydrogenase assembly factor 2, mitochondrial
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:203932 Liu J, et al., Succinate dehydrogenase 5 (SDH5) regulates glycogen synthase kinase 3beta-beta-catenin-mediated lung cancer metastasis. J Biol Chem. 2013 Oct 11;288(41):29965-73
All references(30)
Other
accession IDs
MGI:2147428, MGI:2147695

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory