About   Help   FAQ
Hsd17b14 Gene Detail
Summary
  • Symbol
    Hsd17b14
  • Name
    hydroxysteroid (17-beta) dehydrogenase 14
  • Synonyms
    0610039E24Rik, Dhrs10, retSDR3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913315
    NCBI Gene: 66065
Location & Maps
more
  • Sequence Map
    Chr7:45554893-45567752 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12860 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 29.35 cM, cytoband B2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    HSD17B14, hydroxysteroid 17-beta dehydrogenase 14
  • Vertebrate Orthologs
    8
  • Human Ortholog
    HSD17B14, hydroxysteroid 17-beta dehydrogenase 14
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DHRS10, retSDR3, SDR47C1
  • Links
    NCBI Gene ID: 51171
    neXtProt AC: NX_Q9BPX1

  • Chr Location
    19q13.33; chr19:48813017-48836703 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021062 VEGA Gene Model | MGI Sequence Detail 12860 C57BL/6J ±  kb
transcript OTTMUST00000049820 VEGA | MGI Sequence Detail 1400 Not Applicable  
polypeptide OTTMUSP00000023146 VEGA | MGI Sequence Detail 273 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    118 from dbSNP Build 142
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR016040 NAD(P)-binding domain
    IPR020904 Short-chain dehydrogenase/reductase, conserved site
    IPR002347 Short-chain dehydrogenase/reductase SDR
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 4
References
more
  • Summaries
    All 27
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/29/2016
MGI 6.06
The Jackson Laboratory