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Sf3b6 Gene Detail
Summary
  • Symbol
    Sf3b6
  • Name
    splicing factor 3B, subunit 6
  • Synonyms
    0610009D07Rik, 6030419K15Rik, Sf3b14
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913305
    NCBI Gene: 66055
  • Gene Overview
    MyGene.info: SF3B6
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:4817608-4827659 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 2.09 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    52 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913305
protein coding gene Chr12:4817544-4827659 (.)
129S1/SvImJ MGP_129S1SvImJ_G0019574
protein coding gene Chr12:1728899-1738895 (+)
A/J MGP_AJ_G0019541
protein coding gene Chr12:1694349-1704367 (+)
AKR/J MGP_AKRJ_G0019511
protein coding gene Chr12:1886977-1896889 (+)
BALB/cJ MGP_BALBcJ_G0019516
protein coding gene Chr12:1733772-1743653 (+)
C3H/HeJ MGP_C3HHeJ_G0019322
protein coding gene Chr12:1661841-1671983 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019965
protein coding gene Chr12:1773418-1783478 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017590
protein coding gene Chr12:1682124-1691578 (+)
CAST/EiJ MGP_CASTEiJ_G0018877
protein coding gene Chr12:1745753-1760253 (+)
CBA/J MGP_CBAJ_G0019293
protein coding gene Chr12:2082188-2091999 (+)
DBA/2J MGP_DBA2J_G0019406
protein coding gene Chr12:1627491-1639275 (+)
FVB/NJ MGP_FVBNJ_G0019397
protein coding gene Chr12:1637690-1647439 (+)
LP/J MGP_LPJ_G0019477
protein coding gene Chr12:1733902-1743803 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019430
protein coding gene Chr12:1827774-1839692 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020004
protein coding gene Chr12:1702595-1713599 (+)
PWK/PhJ MGP_PWKPhJ_G0018643
protein coding gene Chr12:1687266-1697913 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018434
protein coding gene Chr12:1734755-1745254 (+)
WSB/EiJ MGP_WSBEiJ_G0018928
protein coding gene Chr12:1694808-1706396 (+)



Homology
more
  • Human Ortholog
    SF3B6, splicing factor 3b subunit 6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SF3B6, splicing factor 3b subunit 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CGI-110, HSPC175, Ht006, P14, SAP14, SAP14a, SF3B14, SF3B14a
  • Links
    NCBI Gene ID: 51639
    neXtProt AC: NX_Q9Y3B4
    UniProt: Q9Y3B4

  • Chr Location
    2p23.3; chr2:24067584-24076444 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9360
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SF3B6
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66055 NCBI Gene Model | MGI Sequence Detail 10052 C57BL/6J ±  kb
transcript NM_025323 RefSeq | MGI Sequence Detail 1133 FVB/N  
polypeptide P59708 UniProt | EBI | MGI Sequence Detail 125 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 133
    cDNA 131
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:1924972, MGI:2142728
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:244597 Cui W, et al., Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos. Sci Rep. 2016 Nov 21;6:37396

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory