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Sdhc
Gene Detail
 Symbol
Name
ID
Sdhc
succinate dehydrogenase complex, subunit C, integral membrane protein
MGI:1913302
Synonyms 0610010E03Rik
Feature Type protein coding gene
Genetic Map
Chromosome 1
78.99 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr1:171127165-171150603 bp, - strand
From VEGA annotation of GRCm38

  23439 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2256  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 3 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: succinate dehydrogenase, cytochrome b560 subunit
Gene Tree: Sdhc

Human
homologs
Human Homolog SDHC, succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
NCBI Gene ID 6391
neXtProt AC  NX_Q99643
Human Synonyms  CYB560, CYBL, PGL3, QPS1, SDH3
Human Chr (Location)  1q23.3; chr1:161314376-161364751 (+)  GRCh38
Disease Associations  (3) Diseases Associated with Human SDHC
Mutations,
alleles, and
phenotypes
All mutations/alleles(209) : Gene trapped(207) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Sdhc interacts with 241 markers (Mir7-1, Mir7b, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process oxidation-reduction process, transport, ...
Component integral component of membrane, membrane, ...
Function electron carrier activity, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (120)    Tissues (99)    Images (22)
Theiler Stages: 22
Assay TypeResults
RNA in situ 120
cDNA source data(323)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(326) cDNA(325) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000021661 (Evidence)
Ensembl Gene ModelENSMUSG00000058076 (Evidence)
Entrez Gene66052 (Evidence)
UniGene198138
DFCITC1573482
DoTSDT.101222113, DT.496432, DT.55166743
NIA Mouse Gene IndexU022044
Consensus CDS ProjectCCDS35772.1
International Mouse Knockout Project StatusSdhc
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021661 VEGA Gene Model | MGI Sequence Detail 23439 C57BL/6J ±  kb
transcript OTTMUST00000051420 VEGA | MGI Sequence Detail 3171 Not Applicable 
polypeptide OTTMUSP00000024190 VEGA | MGI Sequence Detail 169 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(4) UniProt(4)
Polymorphisms SNPs within 2kb(317 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014314 Succinate dehydrogenase, cytochrome b556 subunit
InterPro IPR014361 Succinate dehydrogenase, cytochrome b560 subunit
InterPro IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site
InterPro IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit
Protein Ontology PR:000014565 succinate dehydrogenase cytochrome b560 subunit, mitochondrial
References (Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(46)
Other
accession IDs
MGI:2138200, MGI:2138435

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory