Sdhc
Gene Detail

Symbol Name ID

Sdhc succinate dehydrogenase complex, subunit C, integral membrane protein MGI:1913302

Synonyms

0610010E03Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 1

78.99 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr1:171127165-171150603 bp, - strand From VEGA annotation of GRCm38   23439 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:2256  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 3 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: succinate dehydrogenase, cytochrome b560 subunit
Gene Tree: Sdhc

Human homologs

Human Homolog		SDHC, succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
NCBI Gene ID		6391
neXtProt AC		NX_Q99643
Human Synonyms		CYB560, CYBL, PGL3, QPS1, SDH3
Human Chr (Location)		1q23.3; chr1:161284166-161334541 (+)  GRCh37.p10
Disease Associations		(3) Diseases Associated with Human SDHC

Alleles and phenotypes

All alleles(209) : Targeted(2) Gene trapped(207)

Gene Ontology (GO) classifications

All GO classifications: (14 annotations)

Process	electron transport chain, transport, ...
Component	integral to membrane, membrane, ...
Function	electron carrier activity, metal ion binding, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (120)    Tissues (99)    Images (22)
Theiler Stages: 22

Assay Type	Results
RNA in situ	120

cDNA source data(322)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(325) cDNA(324) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000021661 (Evidence)
Ensembl Gene Model	ENSMUSG00000058076 (Evidence)
Entrez Gene	66052 (Evidence)
UniGene	198138
DFCI	TC1573482
DoTS	DT.101222113, DT.496432, DT.55166743
NIA Mouse Gene Index	U022044
Consensus CDS Project	CCDS35772.1
International Mouse Knockout Project Status	Sdhc

Sequences

Length	Strain/Species
genomic	OTTMUSG00000021661	VEGA Gene Model | MGI Sequence Detail	23439	C57BL/6J
transcript	OTTMUST00000051420	VEGA | MGI Sequence Detail	3171	Not Applicable
polypeptide	OTTMUSP00000024190	VEGA | MGI Sequence Detail	169	Not Applicable

All sequences(38) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(132 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR014314	Succinate dehydrogenase, cytochrome b556 subunit
InterPro	IPR014361	Succinate dehydrogenase, cytochrome b560 subunit
InterPro	IPR018495	Succinate dehydrogenase, cytochrome b subunit, conserved site
InterPro	IPR000701	Succinate dehydrogenase/Fumarate reductase, transmembrane subunit
Protein Ontology	PR:000014565	succinate dehydrogenase cytochrome b560 subunit, mitochondrial

References

(Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(46)

Other accession IDs

MGI:2138200, MGI:2138435