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Dtd1 Gene Detail
Summary
  • Symbol
    Dtd1
  • Name
    D-tyrosyl-tRNA deacylase 1
  • Synonyms
    0610006H08Rik, Hars2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913294
    NCBI Gene: 66044
Location & Maps
more
  • Sequence Map
    Chr2:144599897-144768758 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      168862 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    DTD1, D-tyrosyl-tRNA deacylase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DTD1, D-tyrosyl-tRNA deacylase 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C20orf88, DUEB, DUE-B, HARS2, pqn-68
  • Links
    NCBI Gene ID: 92675
    neXtProt AC: NX_Q8TEA8

  • Chr Location
    20p11.23; chr20:18587912-18763917 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 5518
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: DTD1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    34
  • Chemically induced (other)
    1
  • Gene trapped
    30
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Dtd1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003939 VEGA Gene Model | MGI Sequence Detail 168862 C57BL/6J ±  kb
transcript OTTMUST00000008734 VEGA | MGI Sequence Detail 1350 Not Applicable  
polypeptide OTTMUSP00000004256 VEGA | MGI Sequence Detail 209 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1296 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000006715 D-tyrosyl-tRNA(Tyr) deacylase 1
  • EC
  • InterPro Domains
    IPR003732 D-aminoacyl-tRNA deacylase DTD
    IPR023509 D-Tyr tRNAtyr deacylase-like domain
Molecular
Reagents
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  • All nucleic 48
    cDNA 48

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:198011 Eom T, et al., NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure. Elife. 2013;2:e00178

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory