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Psmd14 Gene Detail
Summary
  • Symbol
    Psmd14
  • Name
    proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
  • Synonyms
    2610312C03Rik, 3200001M20Rik, Pad1, POH1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913284
    NCBI Gene: 59029
  • Gene Overview
    MyGene.info: PSMD14
Location & Maps
more
  • Sequence Map
    Chr2:61711694-61800376 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      88683 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    PSMD14, proteasome 26S subunit, non-ATPase 14
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PSMD14, proteasome 26S subunit, non-ATPase 14
    Orthology source: HomoloGene
  • Synonyms
    PAD1, POH1, RPN11
  • Links
    NCBI Gene ID: 10213
    neXtProt AC: NX_O00487

  • Chr Location
    2q24.2; chr2:161308275-161411717 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 4240
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: PSMD14
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    52
  • Chemically induced (other)
    1
  • Gene trapped
    49
  • Targeted
    2
  • Genomic Mutations
    1 involving Psmd14
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000013076 VEGA Gene Model | MGI Sequence Detail 88683 C57BL/6J ±  kb
transcript OTTMUST00000031567 VEGA | MGI Sequence Detail 1541 Not Applicable  
polypeptide OTTMUSP00000014073 VEGA | MGI Sequence Detail 310 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    184 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000013386 26S proteasome non-ATPase regulatory subunit 14
  • EC
  • InterPro Domains
    IPR000555 JAB1/MPN/MOV34 metalloenzyme domain
    IPR024969 Rpn11/EIF3F, C-terminal
Molecular
Reagents
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  • All nucleic 164
    cDNA 164

    Microarray probesets 3
Other
Accession IDs
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MGI:1915210, MGI:1919662, MGI:2138822
References
more
  • Summaries
    All 43
    Developmental Gene Expression 4
    Gene Ontology 8
    Phenotypes 10
  • Earliest
    J:64935 Penney M, et al., The Pad1+ gene encodes a subunit of the 26 S proteasome in fission yeast. J Biol Chem. 1998 Sep 11;273(37):23938-45
  • Latest
    J:220583 Nielsen JV, et al., Zbtb20 defines a hippocampal neuronal identity through direct repression of genes that control projection neuron development in the isocortex. Cereb Cortex. 2014 May;24(5):1216-29

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory