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Kcnmb4
Gene Detail
Symbol

Name
ID
Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
MGI:1913272
Synonyms
2900045G12Rik, Slowpoke beta 4
Feature Type
protein coding gene
Genetic Map
Chromosome 10
64.73 cM, cytoband D2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:116417861-116473878 bp, - strand
From VEGA annotation of GRCm38

  56018 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8721  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: KCNMB4
Protein SuperFamily: calcium-activated potassium channel, beta subunit
Gene Tree: Kcnmb4

Human
homologs
KCNMB4, potassium channel subfamily M regulatory beta subunit 4
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 27345
neXtProt AC: NX_Q86W47

Human Chr (Location): 12q; chr12:70366223-70434292 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from APF )
 
Homozygous mutation of this gene results in no obvious phenotype.
 
Interactions
Kcnmb4 interacts with 196 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (130)    Tissues (28)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 130
cDNA source data(6)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase kcnmb4    NEW 
Molecular
reagents
All nucleic(7) cDNA(7)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000036564 (Evidence)
Ensembl Gene Model ENSMUSG00000054934 (Evidence)
Entrez Gene 58802 (Evidence)
DFCI TC1698562, TC1621942, TC1586249
Consensus CDS Project CCDS24184.1
International Mouse Phenotyping Consortium Status Kcnmb4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036564 VEGA Gene Model | MGI Sequence Detail 56018 C57BL/6J ±  kb
transcript OTTMUST00000093773 VEGA | MGI Sequence Detail 1367 Not Applicable 
polypeptide OTTMUSP00000052095 VEGA | MGI Sequence Detail 210 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(4) UniProt(4)
Polymorphisms
SNPs within 2kb(494 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003930 Potassium channel, calcium-activated, BK, beta subunit
Protein Ontology PR:000009269 calcium-activated potassium channel subunit beta-4
References
(Earliest) J:65054 Weiger TM, et al., A novel nervous system beta subunit that downregulates human large conductance calcium-dependent potassium channels. J Neurosci. 2000 May 15;20(10):3563-70
(Latest) J:200818 Wen D, et al., Regulation of BK-alpha expression in the distal nephron by aldosterone and urine pH. Am J Physiol Renal Physiol. 2013 Aug;305(4):F463-76
All references(41)
Other
accession IDs
MGI:1920173

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory