About   Help   FAQ
Hs1bp3
Gene Detail
 Symbol
Name
ID
Hs1bp3
HCLS1 binding protein 3
MGI:1913224
Feature Type protein coding gene
Genetic Map
Chromosome 12
3.85 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr12:8313433-8343824 bp, + strand
From NCBI annotation of GRCm38

  30392 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10980  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Hs1bp3

Human
homologs
Human Homolog HS1BP3, HCLS1 binding protein 3
NCBI Gene ID 64342
neXtProt AC  NX_Q53T59
Human Synonyms  ETM2, HS1-BP3
Human Chr (Location)  2p24.1; chr2:20617804-20651104 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(2) Targeted(2)
Incidental mutations (data from APF )
Interactions
Hs1bp3 interacts with 198 markers (Mir1b, Mir17, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process cell surface receptor signaling pathway, T cell differentiation
Component cellular_component
Function phosphatidylinositol binding, protein binding
External Resources: FuncBase
Expression
cDNA source data(46)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(48) cDNA(46) Other(2)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000020605 (Evidence)
Entrez Gene58240 (Evidence)
UniGene309954
DFCITC1580797, TC1598031, TC1680875
DoTSDT.94200080
NIA Mouse Gene IndexU043256
Consensus CDS ProjectCCDS49024.1
International Mouse Knockout Project StatusHs1bp3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 58240 NCBI Gene Model | MGI Sequence Detail 30392 C57BL/6J ±  kb
transcript NM_021429 RefSeq | MGI Sequence Detail 2958 C57BL/6 
polypeptide Q3TC93 UniProt | EBI | MGI Sequence Detail 395 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(250 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001683 Phox homologous domain
Protein Ontology PR:000008756 HCLS1-binding protein 3
Graphical View of Protein Domain Structure
References (Earliest) J:64960 Takemoto Y, et al., Isolation and characterization of a novel HS1 SH3 domain binding protein, HS1BP3. Int Immunol. 1999 Dec;11(12):1957-64
(Latest) J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/23/2014
MGI 5.19
The Jackson Laboratory