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Il1rl2
Gene Detail
Symbol

Name
ID
Il1rl2
interleukin 1 receptor-like 2
MGI:1913107
Feature Type
protein coding gene
Genetic Map
Chromosome 1
18.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:40324466-40366368 bp, + strand
From NCBI annotation of GRCm38

  41903 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2860  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: interleukin-1 receptor type I
Gene Tree: Il1rl2

Human
homologs
Human Homolog IL1RL2, interleukin 1 receptor-like 2
NCBI Gene ID 8808
neXtProt AC  NX_Q9HB29
Human Synonyms  IL-1Rrp2, IL1R-rp2, IL1RRP2, IL-36R
Human Chr (Location)  2q12; chr2:102186973-102240002 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a reporter allele are viable and overtly normal and have normal skin in an unchallenged context.
 
Phenotype Images(1)
Interactions
Il1rl2 interacts with 14 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
cDNA source data(34)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(34) cDNA(34)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000070942 (Evidence)
Entrez Gene107527 (Evidence)
UniGene155583
DFCITC1590842, TC1604310, TC1628458, TC1657565
DoTSDT.94264616, DT.91386691, DT.91299349, DT.485168
NIA Mouse Gene IndexU000196
Consensus CDS ProjectCCDS14910.1
International Mouse Knockout Project StatusIl1rl2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 107527 NCBI Gene Model | MGI Sequence Detail 41903 C57BL/6J ±  kb
transcript NM_133193 RefSeq | MGI Sequence Detail 1950 C57BL/6 
polypeptide Q9ERS7 UniProt | EBI | MGI Sequence Detail 574 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(10) UniProt(5)
Polymorphisms
SNPs within 2kb(430 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR015621 Interleukin-1 receptor family
InterPro IPR004076 Interleukin-1 receptor IL1R
InterPro IPR004074 Interleukin-1 receptor, type I/II
InterPro IPR000157 Toll/interleukin-1 receptor homology (TIR) domain
Protein Ontology PR:000008995 interleukin-1 receptor-like 2
Graphical View of Protein Domain Structure
References
(Earliest) J:64721 Born TL, et al., Identification and characterization of two members of a novel class of the interleukin-1 receptor (IL-1R) family. DELINEATION OF A NEW CLASS OF IL-1R-RELATED PROTEINS BASED ON SIGNALING. J Biol Chem. 2000 Sep 29;275(39):29946-54
(Latest) J:193548 Tortola L, et al., Psoriasiform dermatitis is driven by IL-36-mediated DC-keratinocyte crosstalk. J Clin Invest. 2012 Nov 1;122(11):3965-76
All references(33)
Other
accession IDs
MGI:2138277, MGI:2138611

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory