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Slc28a2 Gene Detail
Summary
  • Symbol
    Slc28a2
  • Name
    solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
  • Synonyms
    2010208B10Rik, CNT2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913105
    NCBI Gene: 269346
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:122426477-122461137 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 60.63 cM, cytoband E3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    299 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913105
protein coding gene Chr2:122426355-122461137 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026416
protein coding gene Chr2:125457539-125554774 (+)
A/J MGP_AJ_G0026377
protein coding gene Chr2:120310653-120419401 (+)
AKR/J MGP_AKRJ_G0026354
protein coding gene Chr2:123729825-123808461 (+)
BALB/cJ MGP_BALBcJ_G0026390
protein coding gene Chr2:120650105-120706021 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0026836
protein coding gene Chr2:129566196-129648380 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0026114
protein coding gene Chr2:134137019-134225651 (+)
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0026352
protein coding gene Chr2:125661468-125796936 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026232
protein coding gene Chr2:138273986-138417749 (+)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0025133
protein coding gene Chr2:122993461-123014318 (+)
WSB/EiJ MGP_WSBEiJ_G0025668
protein coding gene Chr2:124719539-124791038 (+)



Homology
more
  • Human Ortholog
    SLC28A2, solute carrier family 28 member 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SLC28A2, solute carrier family 28 member 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CNT2, HCNT2, HsT17153, SPNT1
  • Links
    NCBI Gene ID: 9153
    neXtProt AC: NX_O43868
    UniProt: O43868

  • Chr Location
    15q21.1; chr15:45252230-45275934 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027219 Ensembl Gene Model | MGI Sequence Detail 34661 C57BL/6J ±  kb
transcript ENSMUST00000110525 Ensembl | MGI Sequence Detail 3911 Not Applicable  
polypeptide ENSMUSP00000106154 Ensembl | MGI Sequence Detail 660 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR008276 Concentrative nucleoside transporter
    IPR030212 Concentrative nucleoside transporter CNT1/CNT2
    IPR011657 Concentrative nucleoside transporter C-terminal domain
    IPR018270 Concentrative nucleoside transporter, metazoan/bacterial
    IPR002668 Concentrative nucleoside transporter N-terminal domain
    IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain
Molecular
Reagents
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  • All nucleic 13
    Genomic 1
    cDNA 10
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
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MGI:1919339, MGI:2139438
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory