About   Help   FAQ
Slc28a2 Gene Detail
Summary
  • Symbol
    Slc28a2
  • Name
    solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
  • Synonyms
    2010208B10Rik, CNT2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913105
    NCBI Gene: 269346
Location & Maps
more
  • Sequence Map
    Chr2:122426477-122461137 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      34661 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    SLC28A2, solute carrier family 28 member 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SLC28A2, solute carrier family 28 member 2
    Orthology source: HomoloGene
  • Synonyms
    CNT2, HCNT2, HsT17153, SPNT1
  • Links
    NCBI Gene ID: 9153
    neXtProt AC: NX_O43868

  • Chr Location
    15q15; chr15:45252066-45275934 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Slc28a2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015614 VEGA Gene Model | MGI Sequence Detail 34661 C57BL/6J ±  kb
transcript OTTMUST00000037084 VEGA | MGI Sequence Detail 3911 Not Applicable  
polypeptide OTTMUSP00000016629 VEGA | MGI Sequence Detail 660 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    299 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000015052 sodium/nucleoside cotransporter 2
  • InterPro Domains
    IPR008276 Concentrative nucleoside transporter
    IPR030212 Concentrative nucleoside transporter CNT1/CNT2
    IPR011657 Concentrative nucleoside transporter C-terminal domain
    IPR018270 Concentrative nucleoside transporter, metazoan/bacterial
    IPR002668 Concentrative nucleoside transporter N-terminal domain
    IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain
Molecular
Reagents
less
  • All nucleic 12
    Genomic 1
    cDNA 9
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1919339, MGI:2139438
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65053 Patel DH, et al., Cloning, genomic organization and chromosomal localization of the gene encoding the murine sodium-dependent, purine-selective, concentrative nucleoside transporter (CNT2). Gene. 2000 Jan 25;242(1-2):51-8
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/26/2016
MGI 6.03
The Jackson Laboratory