About   Help   FAQ
Psrc1 Gene Detail
Summary
  • Symbol
    Psrc1
  • Name
    proline/serine-rich coiled-coil 1
  • Synonyms
    5430413I02Rik, DDA3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913099
    NCBI Gene: 56742
  • Gene Overview
    MyGene.info: PSRC1
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:108383839-108388231 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 47.01 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    15 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913099
protein coding gene Chr3:108383804-108388231 (.)
129S1/SvImJ MGP_129S1SvImJ_G0027775
protein coding gene Chr3:109932614-109937005 (+)
A/J MGP_AJ_G0027735
protein coding gene Chr3:106443335-106447726 (+)
AKR/J MGP_AKRJ_G0027700
protein coding gene Chr3:109036752-109041143 (+)
BALB/cJ MGP_BALBcJ_G0027747
protein coding gene Chr3:106145193-106149583 (+)
C3H/HeJ MGP_C3HHeJ_G0027477
protein coding gene Chr3:109388481-109392872 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028191
protein coding gene Chr3:114037274-114041665 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025529
protein coding gene Chr3:102591973-102596591 (+)
CAST/EiJ MGP_CASTEiJ_G0026933
protein coding gene Chr3:108770914-108776250 (+)
CBA/J MGP_CBAJ_G0027452
protein coding gene Chr3:117918380-117922771 (+)
DBA/2J MGP_DBA2J_G0027594
protein coding gene Chr3:105627876-105632267 (+)
FVB/NJ MGP_FVBNJ_G0027562
protein coding gene Chr3:103512593-103516984 (+)
LP/J MGP_LPJ_G0027701
protein coding gene Chr3:111351028-111355418 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027592
protein coding gene Chr3:123971249-123975642 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028246
protein coding gene Chr3:108635993-108640417 (+)
PWK/PhJ MGP_PWKPhJ_G0026659
protein coding gene Chr3:105376904-105381410 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026479
protein coding gene Chr3:106774608-106779190 (+)
WSB/EiJ MGP_WSBEiJ_G0027013
protein coding gene Chr3:109173129-109177519 (+)



Homology
more
  • Human Ortholog
    PSRC1, proline and serine rich coiled-coil 1
  • Vertebrate Orthologs
    6
  • Human Ortholog
    PSRC1, proline and serine rich coiled-coil 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DDA3, FP3214
  • Links
    NCBI Gene ID: 84722
    neXtProt AC: NX_Q6PGN9
    UniProt: Q6PGN9

  • Chr Location
    1p13.3; chr1:109279554-109283182 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000068744 Ensembl Gene Model | MGI Sequence Detail 4393 C57BL/6J ±  kb
transcript ENSMUST00000090561 Ensembl | MGI Sequence Detail 1686 Not Applicable  
polypeptide ENSMUSP00000088049 Ensembl | MGI Sequence Detail 329 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000013406 proline/serine-rich coiled-coil protein 1
  • InterPro Domains
    IPR032768 G2 and S phase-expressed protein 1, N-terminal
    IPR026658 Proline/serine-rich coiled-coil protein 1
    IPR026657 Proline/serine-rich coiled-coil protein 1/G2 and S phase-expressed protein 1
Molecular
Reagents
less
  • All nucleic 98
    cDNA 98

    Microarray probesets 5
Other
Accession IDs
less
MGI:1914808, MGI:2139859
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:64940 Lo PK, et al., Identification of a novel mouse p53 target gene DDA3. Oncogene. 1999 Dec 16;18(54):7765-74
  • Latest
    J:243411 Rutledge EA, et al., Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/13/2018
MGI 6.13
The Jackson Laboratory