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Ywhab Gene Detail
Summary
  • Symbol
    Ywhab
  • Name
    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
  • Synonyms
    1300003C17Rik, 14-3-3b, 14-3-3 beta
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891917
    NCBI Gene: 54401
  • Gene Overview
    MyGene.info: YWHAB
Location & Maps
more
  • Sequence Map
    Chr2:163994960-164018588 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      23629 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 84.59 cM, cytoband H3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    YWHAB, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
  • Vertebrate Orthologs
    11
  • Human Ortholog
    YWHAB, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GW128, HEL-S-1, HS1, KCIP-1, YWHAA
  • Links
    NCBI Gene ID: 7529
    neXtProt AC: NX_P31946

  • Chr Location
    20q13.1; chr20:44885599-44908532 (+)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    32
  • Gene trapped
    31
  • Targeted
    1
  • Incidental Mutations
    Mutagenetix , APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    170
  • Tissues
    55
  • cDNA Data
    18
  • Literature Summary
    8
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016138 VEGA Gene Model | MGI Sequence Detail 23629 C57BL/6J ±  kb
transcript OTTMUST00000038595 VEGA | MGI Sequence Detail 3013 Not Applicable  
polypeptide OTTMUSP00000017275 VEGA | MGI Sequence Detail 246 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    123 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 20
    Primer pair 2

    Microarray probesets 7
Other
Accession IDs
less
MGI:1914136
References
more
  • Summaries
    All 53
    Developmental Gene Expression 8
    Gene Ontology 12
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:233111 Dufner A, et al., The ubiquitin-specific protease USP8 is critical for the development and homeostasis of T cells. Nat Immunol. 2015 Sep;16(9):950-60
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory