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Ncbp1
Gene Detail
Symbol

Name
ID
Ncbp1
nuclear cap binding protein subunit 1
MGI:1891840
Feature Type
protein coding gene
Genetic Map
Chromosome 4
24.49 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:46138613-46172403 bp, + strand
From VEGA annotation of GRCm38

  33791 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1859  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: NCBP1
Protein SuperFamily: nuclear cap-binding complex, CBP80 subunit
Gene Tree: Ncbp1

Human
homologs
NCBP1, nuclear cap binding protein subunit 1, 80kDa
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 4686
neXtProt AC: NX_Q09161

Human Synonyms: CBP80, NCBP, Sto1

Human Chr (Location): 9q34.1; chr9:97633423-97673748 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(14) : Gene trapped(12) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Ncbp1 interacts with 109 markers (Mir15b, Mir17, Mir20b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (28 annotations)
Process 7-methylguanosine mRNA capping, gene silencing by RNA, ...
Component cytoplasm, mitochondrion, ...
Function poly(A) RNA binding, protein binding, ...
External Resources: FuncBase
Expression
cDNA source data(12)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ncbp1    NEW 
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000006833 (Evidence)
Ensembl Gene Model ENSMUSG00000028330 (Evidence)
Entrez Gene 433702 (Evidence)
DFCI TC1578321, TC1631429
DoTS DT.94330518, DT.534376, DT.101735474, DT.97384743
NIA Mouse Gene Index U004284
PDB 3UKZ, 3UL0
Consensus CDS Project CCDS18145.1
International Mouse Phenotyping Consortium Status Ncbp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006833 VEGA Gene Model | MGI Sequence Detail 33791 C57BL/6J ±  kb
transcript OTTMUST00000015791 VEGA | MGI Sequence Detail 3010 Not Applicable 
polypeptide OTTMUSP00000007257 VEGA | MGI Sequence Detail 790 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(175 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016024 Armadillo-type fold
InterPro IPR015172 MIF4G-like, type 1
InterPro IPR015174 MIF4G-like, type 2
InterPro IPR003890 MIF4G-like, type 3
InterPro IPR016021 MIF4-like, type 1/2/3
InterPro IPR027159 Nuclear cap-binding protein subunit 1
Protein Ontology PR:000011026 nuclear cap-binding protein subunit 1
References
(Earliest) J:34628 Chadwick BP, et al., Nuclear cap binding protein maps close to the xeroderma pigmentosum complementation group A (XPA) locus in human and mouse. Genomics. 1996 1;35(3):632-3
(Latest) J:185950 Padmanabhan K, et al., Feedback regulation of transcriptional termination by the mammalian circadian clock PERIOD complex. Science. 2012 Aug 3;337(6094):599-602
All references(31)
Other
accession IDs
MGI:2140419, MGI:2140583

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory