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Ncbp1 Gene Detail
Summary
  • Symbol
    Ncbp1
  • Name
    nuclear cap binding protein subunit 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891840
    NCBI Gene: 433702
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:46138613-46172403 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 24.49 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    175 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891840
protein coding gene Chr4:46138511-46172403 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028253
protein coding gene Chr4:44420181-44455661 (+)
A/J MGP_AJ_G0028212
protein coding gene Chr4:42811760-42845466 (+)
AKR/J MGP_AKRJ_G0028162
protein coding gene Chr4:43848340-43883567 (+)
BALB/cJ MGP_BALBcJ_G0028232
protein coding gene Chr4:42908952-42942685 (+)
C3H/HeJ MGP_C3HHeJ_G0027953
protein coding gene Chr4:44451794-44491947 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028673
protein coding gene Chr4:46066932-46102558 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025982
protein coding gene Chr4:40201740-40235745 (+)
CAST/EiJ MGP_CASTEiJ_G0027392
protein coding gene Chr4:44014313-44048974 (+)
CBA/J MGP_CBAJ_G0027919
protein coding gene Chr4:47518608-47558101 (+)
DBA/2J MGP_DBA2J_G0028069
protein coding gene Chr4:42705825-42739976 (+)
FVB/NJ MGP_FVBNJ_G0028036
protein coding gene Chr4:41948584-41982228 (+)
LP/J MGP_LPJ_G0028168
protein coding gene Chr4:44476840-44511649 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028060
protein coding gene Chr4:50624360-50658955 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028708
protein coding gene Chr4:44066333-44102345 (+)
PWK/PhJ MGP_PWKPhJ_G0027117
protein coding gene Chr4:42793974-42828437 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026945
protein coding gene Chr4:43559907-43598439 (+)
WSB/EiJ MGP_WSBEiJ_G0027470
protein coding gene Chr4:43968567-44003602 (+)



Homology
more
  • Human Ortholog
    NCBP1, nuclear cap binding protein subunit 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    NCBP1, nuclear cap binding protein subunit 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CBP80, NCBP, Sto1
  • Links
    NCBI Gene ID: 4686
    neXtProt AC: NX_Q09161
    UniProt: Q09161

  • Chr Location
    9q22.33; chr9:97633423-97673748 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028330 Ensembl Gene Model | MGI Sequence Detail 33791 C57BL/6J ±  kb
transcript ENSMUST00000030014 Ensembl | MGI Sequence Detail 3010 Not Applicable  
polypeptide ENSMUSP00000030014 Ensembl | MGI Sequence Detail 790 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 3
Other
Accession IDs
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MGI:2140419, MGI:2140583
References
more
  • Summaries
    All 33
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:34628 Chadwick BP, et al., Nuclear cap binding protein maps close to the xeroderma pigmentosum complementation group A (XPA) locus in human and mouse. Genomics. 1996 1;35(3):632-3
  • Latest
    J:226985 Gebhardt A, et al., mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3. Nat Commun. 2015;6:8192

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/01/2019
MGI 6.14
The Jackson Laboratory