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Zbtb32
Gene Detail
Symbol

Name
ID
Zbtb32
zinc finger and BTB domain containing 32
MGI:1891838
Synonyms
4930524C15Rik, PLZP, Rog, Tzfp
Feature Type
protein coding gene
Genetic Map
Chromosome 7
18.72 cM, cytoband B2-B3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:30589681-30598909 bp, - strand
From VEGA annotation of GRCm38

  9229 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8661  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: ZBTB32
Gene Tree: Zbtb32

Human
homologs
ZBTB32, zinc finger and BTB domain containing 32
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 27033
neXtProt AC: NX_Q9Y2Y4

Human Synonyms: FAXF, FAZF, Rog, TZFP, ZNF538

Human Chr (Location): 19q13.1; chr19:35704492-35717048 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(30) : Gene trapped(23) Targeted(7)
Incidental mutations (data from Mutagenetix )
 
Homozygous null mice display increased T cell proliferation and increased cytokine secretion.
 
Interactions
Zbtb32 interacts with 39 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process hemopoiesis, negative regulation of nucleic acid-templated transcription, ...
Component nuclear chromosome, nucleus
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (14)    Tissues (7)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 14
cDNA source data(4)
Other mouse links: GEO   Expression Atlas
Molecular
reagents
All nucleic(7) Genomic(1) cDNA(5) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000023052 (Evidence)
Ensembl Gene Model ENSMUSG00000006310 (Evidence)
Entrez Gene 58206 (Evidence)
DFCI TC1587349, TC1595342, TC1646259, TC1727683
DoTS DT.40177493, DT.91296870, DT.91588802
NIA Mouse Gene Index U028392
PDB 2KVF, 2KVG, 2KVH
Consensus CDS Project CCDS21102.1
International Mouse Phenotyping Consortium Status Zbtb32
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023052 VEGA Gene Model | MGI Sequence Detail 9229 C57BL/6J ±  kb
transcript OTTMUST00000055563 VEGA | MGI Sequence Detail 1775 Not Applicable 
polypeptide OTTMUSP00000026619 VEGA | MGI Sequence Detail 465 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(10) UniProt(2)
Polymorphisms
SNPs within 2kb(97 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000210 BTB/POZ domain
InterPro IPR011333 POZ domain
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000017574 zinc finger and BTB domain-containing protein 32
References
(Earliest) J:64944 Miaw SC, et al., ROG, repressor of GATA, regulates the expression of cytokine genes. Immunity. 2000 Mar;12(3):323-33
(Latest) J:200878 Furu K, et al., Tzfp represses the androgen receptor in mouse testis. PLoS One. 2013;8(4):e62314
All references(44)
Other
accession IDs
MGI:1922359

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory