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Pfkp Gene Detail
Summary
  • Symbol
    Pfkp
  • Name
    phosphofructokinase, platelet
  • Synonyms
    1200015H23Rik, 9330125N24Rik, PFK-C
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891833
    NCBI Gene: 56421
  • Gene Overview
    MyGene.info: PFKP
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:6579874-6648792 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 3.25 cM, cytoband A1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    760 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891833
protein coding gene Chr13:6579768-6648792 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020215
protein coding gene Chr13:3153902-3221366 (-)
A/J MGP_AJ_G0020171
protein coding gene Chr13:3183018-3250030 (-)
AKR/J MGP_AKRJ_G0020146
protein coding gene Chr13:3258520-3322849 (-)
BALB/cJ MGP_BALBcJ_G0020154
protein coding gene Chr13:3173965-3239609 (-)
C3H/HeJ MGP_C3HHeJ_G0019958
protein coding gene Chr13:3342803-3405524 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020601
protein coding gene Chr13:3345572-3409362 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018211
protein coding gene Chr13:3078777-3142647 (-)
CAST/EiJ MGP_CASTEiJ_G0019498
protein coding gene Chr13:3133902-3197134 (-)
CBA/J MGP_CBAJ_G0019925
protein coding gene Chr13:3411244-3476460 (-)
DBA/2J MGP_DBA2J_G0020042
protein coding gene Chr13:3092954-3155051 (-)
FVB/NJ MGP_FVBNJ_G0020027
protein coding gene Chr13:2970210-3039908 (-)
LP/J MGP_LPJ_G0020116
protein coding gene Chr13:3302065-3373213 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020063
protein coding gene Chr13:3648756-3719621 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020629
protein coding gene Chr13:3210826-3275142 (-)
PWK/PhJ MGP_PWKPhJ_G0019258
protein coding gene Chr13:2952391-3188024 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019066
protein coding gene Chr13:3277682-3345419 (-)
WSB/EiJ MGP_WSBEiJ_G0019556
protein coding gene Chr13:3143717-3207083 (-)



Homology
more
  • Human Ortholog
    PFKP, phosphofructokinase, platelet
  • Vertebrate Orthologs
    8
  • Human Ortholog
    PFKP, phosphofructokinase, platelet
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ATP-PFK, PFK-C, PFKF, PFK-P
  • Links
    NCBI Gene ID: 5214
    neXtProt AC: NX_Q01813
    UniProt: Q01813

  • Chr Location
    10p15.2; chr10:3067475-3136805 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56421 NCBI Gene Model | MGI Sequence Detail 68919 C57BL/6J ±  kb
transcript NM_019703 RefSeq | MGI Sequence Detail 4033 C57BL/6  
polypeptide Q9WUA3 UniProt | EBI | MGI Sequence Detail 784 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    cDNA 25
    Primer pair 2

    Microarray probesets 7
Other
Accession IDs
less
MGI:1921374, MGI:1924805
References
more
  • Summaries
    All 54
    Developmental Gene Expression 14
    Gene Ontology 9
    Phenotypes 9
  • Earliest
    J:139710 Gekakis N, et al., Phosphofructokinase isozyme expression during myoblast differentiation. J Biol Chem. 1989 Mar 5;264(7):3658-61
  • Latest
    J:243134 Lowther KM, et al., Embryonic poly(A)-binding protein is required at the preantral stage of mouse folliculogenesis for oocyte-somatic communication. Biol Reprod. 2017 Feb 01;96(2):341-351

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory