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Pfkp Gene Detail
Summary
  • Symbol
    Pfkp
  • Name
    phosphofructokinase, platelet
  • Synonyms
    1200015H23Rik, 9330125N24Rik, PFK-C
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891833
    NCBI Gene: 56421
  • Gene Overview
    MyGene.info: PFKP
Location & Maps
more
  • Sequence Map
    Chr13:6579768-6648777 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      69010 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 3.25 cM, cytoband A1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PFKP, phosphofructokinase, platelet
  • Vertebrate Orthologs
    8
  • Human Ortholog
    PFKP, phosphofructokinase, platelet
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ATP-PFK, PFK-C, PFKF, PFK-P
  • Links
    NCBI Gene ID: 5214
    neXtProt AC: NX_Q01813

  • Chr Location
    10p15.3-p15.2; chr10:3067474-3136805 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033856 VEGA Gene Model | MGI Sequence Detail 69010 C57BL/6J ±  kb
transcript OTTMUST00000085331 VEGA | MGI Sequence Detail 2679 Not Applicable  
polypeptide OTTMUSP00000046091 VEGA | MGI Sequence Detail 784 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    761 from dbSNP Build 142
Protein
Information
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  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000012584 ATP-dependent 6-phosphofructokinase, platelet type
  • EC
  • InterPro Domains
    IPR022953 ATP-dependent 6-phosphofructokinase
    IPR009161 ATP-dependent 6-phosphofructokinase, eukaryotic-type
    IPR015912 Phosphofructokinase, conserved site
    IPR000023 Phosphofructokinase domain
Molecular
Reagents
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  • All nucleic 26
    cDNA 24
    Primer pair 2

    Microarray probesets 7
Other
Accession IDs
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MGI:1921374, MGI:1924805
References
more
  • Summaries
    All 48
    Developmental Gene Expression 12
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:139710 Gekakis N, et al., Phosphofructokinase isozyme expression during myoblast differentiation. J Biol Chem. 1989 Mar 5;264(7):3658-61
  • Latest
    J:195239 Ahmed SM, et al., KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression. J Cell Biol. 2012 Dec 10;199(6):951-67

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory