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Gps2
Gene Detail
Symbol

Name
ID
Gps2
G protein pathway suppressor 2
MGI:1891751
Feature Type
protein coding gene
Genetic Map
Chromosome 11
42.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:69913888-69916591 bp, + strand
From VEGA annotation of GRCm38

  2704 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:49599  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: GPS2
Gene Tree: Gps2

Human
homologs
GPS2, G protein pathway suppressor 2
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 2874
neXtProt AC: NX_Q13227

Human Synonyms: AMF-1

Human Chr (Location): 17p13; chr17:7312659-7315339 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(1) Targeted(1)
Genomic Mutations involving Gps2 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Gps2 interacts with 26 markers (Mir29b-1, Mir133a-1, Mir133a-2, ...)
Expression
cDNA source data(79)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase gps2 ; ZFIN gps2    NEW 
Molecular
reagents
All nucleic(79) cDNA(79)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000006026 (Evidence)
Ensembl Gene Model ENSMUSG00000023170 (Evidence)
Entrez Gene 56310 (Evidence)
UniGene 477738
DFCI TC1580898, TC1754638
DoTS DT.94248276, DT.530625
NIA Mouse Gene Index U157216
Consensus CDS Project CCDS24922.1
International Mouse Phenotyping Consortium Status Gps2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006026 VEGA Gene Model | MGI Sequence Detail 2704 C57BL/6J ±  kb
transcript OTTMUST00000037515 VEGA | MGI Sequence Detail 1311 Not Applicable 
polypeptide OTTMUSP00000016813 VEGA | MGI Sequence Detail 327 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(14) UniProt(3)
Polymorphisms
SNPs within 2kb(24 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026094 G protein pathway suppressor 2
Protein Ontology PR:000008203 G protein pathway suppressor 2
References
(Earliest) J:91812 Stryke D, et al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Res. 2003 Jan 1;31(1):278-81
(Latest) J:135288 Zhang D, et al., G-protein pathway suppressor 2 (GPS2) interacts with the regulatory factor X4 variant 3 (RFX4_v3) and functions as a transcriptional co-activator. J Biol Chem. 2008 Mar 28;283(13):8580-90
All references(25)
Other
accession IDs
MGI:2144211

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory