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Mycbp Gene Detail
Summary
  • Symbol
    Mycbp
  • Name
    MYC binding protein
  • Synonyms
    5730488M09Rik, Amy-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891750
    NCBI Gene: 56309
  • Gene Overview
    MyGene.info: MYCBP
Location & Maps
more
  • Sequence Map
    Chr4:123904832-123912269 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7438 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 57.42 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    MYCBP, MYC binding protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MYCBP, MYC binding protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AMY-1
  • Links
    NCBI Gene ID: 26292
    neXtProt AC: NX_Q99417

  • Chr Location
    1p33-p32.2; chr1:38862490-38873378 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 49312
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: MYCBP
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    2
  • Gene trapped
    7
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    4 involving Mycbp
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008990 VEGA Gene Model | MGI Sequence Detail 7438 C57BL/6J ±  kb
transcript OTTMUST00000020407 VEGA | MGI Sequence Detail 1536 Not Applicable  
polypeptide OTTMUSP00000009357 VEGA | MGI Sequence Detail 146 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    26 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR026060 Associate of Myc 1
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 7
Other
Accession IDs
less
MGI:1915499, MGI:2140596, MGI:2140609
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:217391 Lin C, et al., Regulation of Sufu activity by p66beta and Mycbp provides new insight into vertebrate Hedgehog signaling. Genes Dev. 2014 Nov 15;28(22):2547-63

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory