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Myl10 Gene Detail
Summary
  • Symbol
    Myl10
  • Name
    myosin, light chain 10, regulatory
  • Synonyms
    1700027I08Rik, Mylc2pl, PLRLC, PLRLC-A, PLRLC-B, PLRLC-C
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891705
    NCBI Gene: 59310
  • Alliance
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:136693146-136701094 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 76.03 cM, cytoband G1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    164 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891705
protein coding gene Chr5:136688892-136701857 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030207
protein coding gene Chr5:141366073-141375985 (+)
A/J MGP_AJ_G0030175
protein coding gene Chr5:135262866-135270494 (+)
AKR/J MGP_AKRJ_G0030108
protein coding gene Chr5:139630158-139643200 (+)
BALB/cJ MGP_BALBcJ_G0030185
protein coding gene Chr5:136617818-136625909 (+)
C3H/HeJ MGP_C3HHeJ_G0029901
protein coding gene Chr5:140249470-140257128 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032461
protein coding gene Chr7:30236858-30240173 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027858
protein coding gene Chr5:129542884-129549176 (+)
CAST/EiJ MGP_CASTEiJ_G0029311
protein coding gene Chr5:139653283-139663281 (+)
CBA/J MGP_CBAJ_G0029871
protein coding gene Chr5:152312638-152323741 (+)
DBA/2J MGP_DBA2J_G0030022
protein coding gene Chr5:135158807-135166466 (+)
FVB/NJ MGP_FVBNJ_G0029977
protein coding gene Chr5:134331280-134338919 (+)
LP/J MGP_LPJ_G0030111
protein coding gene Chr5:141791026-141800432 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030009
protein coding gene Chr5:155270606-155278258 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030678
protein coding gene Chr5:139456885-139464884 (+)
PWK/PhJ MGP_PWKPhJ_G0029024
protein coding gene Chr5:134237896-134246281 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028860
protein coding gene Chr5:137035935-137043674 (+)
WSB/EiJ MGP_WSBEiJ_G0029384
protein coding gene Chr5:140187669-140197498 (+)



Homology
more
  • Human Ortholog
    MYL10, myosin light chain 10
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MYL10, myosin light chain 10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MYLC2PL, PLRLC
  • Links
    NCBI Gene ID: 93408
    neXtProt AC: NX_Q9BUA6
    UniProt: Q9BUA6

  • Chr Location
    7q22.1; chr7:101613325-101629296 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 69341
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MYL10
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000005474 Ensembl Gene Model | MGI Sequence Detail 7949 C57BL/6J ±  kb
transcript ENSMUST00000005611 Ensembl | MGI Sequence Detail 688 Not Applicable  
polypeptide ENSMUSP00000005611 Ensembl | MGI Sequence Detail 147 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 3
Other
Accession IDs
less
MGI:1917247
References
more
  • Summaries
    All 23
    Gene Ontology 5
    Phenotypes 2
  • Earliest
    J:1334 Oltz EM, et al., A novel regulatory myosin light chain gene distinguishes pre-B cell subsets and is IL-7 inducible. EMBO J. 1992 Jul;11(7):2759-67
  • Latest
    J:214070 Grossman GH, et al., Protein partners of dynamin-1 in the retina. Vis Neurosci. 2013 Jul;30(4):129-39

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory