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Myl10 Gene Detail
Summary
  • Symbol
    Myl10
  • Name
    myosin, light chain 10, regulatory
  • Synonyms
    1700027I08Rik, Mylc2pl, PLRLC, PLRLC-A, PLRLC-B, PLRLC-C
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891705
    NCBI Gene: 59310
Location & Maps
more
  • Sequence Map
    Chr5:136693146-136701094 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7949 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 76.03 cM, cytoband G1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    MYL10, myosin light chain 10
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MYL10, myosin light chain 10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MYLC2PL, PLRLC
  • Links
    NCBI Gene ID: 93408
    neXtProt AC: NX_Q9BUA6

  • Chr Location
    7q22.1; chr7:101613325-101629296 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 69341
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: MYL10
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
  • All Mutations and Alleles
    1
  • Targeted
    1
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Other Mouse Links
  • Other Vertebrate Links
    Xenbase myl10
    ZFIN myl10
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000054396 VEGA Gene Model | MGI Sequence Detail 7949 C57BL/6J ±  kb
transcript OTTMUST00000134949 VEGA | MGI Sequence Detail 688 Not Applicable  
polypeptide OTTMUSP00000071513 VEGA | MGI Sequence Detail 147 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    164 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000010843 myosin light chain 2, lymphocyte-specific
  • InterPro Domains
    IPR018247 EF-Hand 1, calcium-binding site
    IPR002048 EF-hand domain
    IPR011992 EF-hand domain pair
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 3
Other
Accession IDs
less
MGI:1917247
References
more
  • Summaries
    All 24
    Gene Ontology 5
    Phenotypes 1
  • Earliest
    J:1334 Oltz EM, et al., A novel regulatory myosin light chain gene distinguishes pre-B cell subsets and is IL-7 inducible. EMBO J. 1992 Jul;11(7):2759-67
  • Latest
    J:214070 Grossman GH, et al., Protein partners of dynamin-1 in the retina. Vis Neurosci. 2013 Jul;30(4):129-39

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory