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Gkap1 Gene Detail
Summary
  • Symbol
    Gkap1
  • Name
    G kinase anchoring protein 1
  • Synonyms
    42kDa, 4933400B15Rik, D13Ertd340e, Gkap42
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891694
    NCBI Gene: 56278
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:58233346-58274839 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 30.97 cM, cytoband B2
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    182 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891694
protein coding gene Chr13:58233346-58275699 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020630
protein coding gene Chr13:57861654-57907174 (-)
A/J MGP_AJ_G0020584
protein coding gene Chr13:55714544-55757198 (-)
AKR/J MGP_AKRJ_G0020562
protein coding gene Chr13:57376886-57420806 (-)
BALB/cJ MGP_BALBcJ_G0020580
protein coding gene Chr13:55965852-56006969 (-)
C3H/HeJ MGP_C3HHeJ_G0020379
protein coding gene Chr13:57184988-57227238 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021014
protein coding gene Chr13:59640658-59685206 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018596
protein coding gene Chr13:53618058-53656248 (-)
CAST/EiJ MGP_CASTEiJ_G0019893
protein coding gene Chr13:57307962-57353312 (-)
CBA/J MGP_CBAJ_G0020339
protein coding gene Chr13:61889051-61935810 (-)
DBA/2J MGP_DBA2J_G0020462
protein coding gene Chr13:55256322-55297312 (-)
FVB/NJ MGP_FVBNJ_G0020441
protein coding gene Chr13:54743830-54785924 (-)
LP/J MGP_LPJ_G0020538
protein coding gene Chr13:58138319-58184465 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020470
protein coding gene Chr13:61257407-61300416 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021057
protein coding gene Chr13:56976032-57019040 (-)
PWK/PhJ MGP_PWKPhJ_G0019649
protein coding gene Chr13:55271120-55314669 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019476
protein coding gene Chr13:55887342-55931027 (-)
WSB/EiJ MGP_WSBEiJ_G0019955
protein coding gene Chr13:57417148-57460941 (-)



Homology
more
  • Human Ortholog
    GKAP1, G kinase anchoring protein 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GKAP1, G kinase anchoring protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FKSG21, GKAP42
  • Links
    NCBI Gene ID: 80318
    neXtProt AC: NX_Q5VSY0
    UniProt: Q5VSY0

  • Chr Location
    9q21.32; chr9:83739421-83817837 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 10515
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: GKAP1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56278 NCBI Gene Model | MGI Sequence Detail 41494 C57BL/6J ±  kb
transcript NM_019832 RefSeq | MGI Sequence Detail 1534 Not Specified  
polypeptide Q9JMB0 UniProt | EBI | MGI Sequence Detail 366 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 42
    cDNA 41
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1196444, MGI:1918285
References
more
  • Summaries
    All 35
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:265598 Ando Y, et al., Tumor necrosis factor (TNF)-alpha-induced repression of GKAP42 protein levels through cGMP-dependent kinase (cGK)-Ialpha causes insulin resistance in 3T3-L1 adipocytes. J Biol Chem. 2015 Feb 27;290(9):5881-92

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory