About   Help   FAQ
Hnrnpr Gene Detail
Summary
  • Symbol
    Hnrnpr
  • Name
    heterogeneous nuclear ribonucleoprotein R
  • Synonyms
    2610003J05Rik, 2610528B01Rik, hnRNPR, Hnrpr
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891692
    NCBI Gene: 74326
  • Gene Overview
    MyGene.info: HNRNPR
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:136310942-136345981 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 68.40 cM, cytoband D3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    216 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891692
protein coding gene Chr4:136310942-136359447 (.)
129S1/SvImJ MGP_129S1SvImJ_G0028965
protein coding gene Chr4:138854710-138909899 (+)
A/J no annotation
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0028948
protein coding gene Chr4:133602767-133652064 (+)
C3H/HeJ MGP_C3HHeJ_G0028662
protein coding gene Chr4:137060568-137110589 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029389
protein coding gene Chr4:143797244-143881632 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026660
protein coding gene Chr4:125981729-126031658 (+)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0028627
protein coding gene Chr4:147717001-147783201 (+)
DBA/2J MGP_DBA2J_G0028776
protein coding gene Chr4:133359231-133408577 (+)
FVB/NJ MGP_FVBNJ_G0028743
protein coding gene Chr4:132303786-132351795 (+)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0028769
protein coding gene Chr4:151948340-152003377 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029427
protein coding gene Chr4:137247051-137300264 (+)
PWK/PhJ MGP_PWKPhJ_G0027814
protein coding gene Chr4:130137258-130188427 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0028172
protein coding gene Chr4:137414419-137464488 (+)



Homology
more
  • Human Ortholog
    HNRNPR, heterogeneous nuclear ribonucleoprotein R
  • Vertebrate Orthologs
    8
  • Human Ortholog
    HNRNPR, heterogeneous nuclear ribonucleoprotein R
    Orthology source: HomoloGene, HGNC
  • Synonyms
    hnRNP-R, HNRPR
  • Links
    NCBI Gene ID: 10236
    neXtProt AC: NX_O43390
    UniProt: O43390

  • Chr Location
    1p36.12; chr1:23304688-23344650 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74326 NCBI Gene Model | MGI Sequence Detail 35040 C57BL/6J ±  kb
transcript NM_001355182 RefSeq | MGI Sequence Detail 8027 C57BL/6  
polypeptide NP_001342111 RefSeq | MGI Sequence Detail 632 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    13 Sequences
  • InterPro Domains
    IPR034410 Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 1
    IPR034411 Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2
    IPR006535 HnRNP R/Q splicing factor
    IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
    IPR035979 RNA-binding domain superfamily
    IPR000504 RNA recognition motif domain
Molecular
Reagents
less
  • All nucleic 23
    cDNA 22
    Primer pair 1

    Microarray probesets 10
Other
Accession IDs
less
MGI:1917292, MGI:1921576
References
more
  • Summaries
    All 44
    Developmental Gene Expression 7
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:64914 Mizutani A, et al., SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms. J Biol Chem. 2000 Mar 31;275(13):9823-31
  • Latest
    J:261272 Briese M, et al., hnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneurons. Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):E2859-E2868

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory