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Dctn5
Gene Detail
Symbol

Name
ID
Dctn5
dynactin 5
MGI:1891689
Synonyms
4930427E12Rik, b2b315Clo, p25 dynactin subunit
Feature Type
protein coding gene
Genetic Map
Chromosome 7
65.47 cM, cytoband F3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:122133041-122149044 bp, + strand
From VEGA annotation of GRCm38

  16004 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10998  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DCTN5
Gene Tree: Dctn5

Human
homologs
DCTN5, dynactin 5 (p25)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 84516
neXtProt AC: NX_Q9BTE1

Human Chr (Location): 16p12.2; chr16:23641366-23673747 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Chemically induced (ENU)(1) Gene trapped(7) Targeted(4)
Incidental mutations (data from APF , CvDC )
Phenotype Images(12)
Interactions
Dctn5 interacts with 99 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process biological_process
Component centrosome, chromosome, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (27)    Tissues (5)    Images (17)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 27
cDNA source data(108)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase dctn5 ; ZFIN dctn5    NEW 
Molecular
reagents
All nucleic(108) cDNA(108)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000022642 (Evidence)
Ensembl Gene Model ENSMUSG00000030868 (Evidence)
Entrez Gene 59288 (Evidence)
UniGene 478285
DFCI TC1574516, TC1585355
DoTS DT.534787, DT.94348446, DT.94348466
NIA Mouse Gene Index U343183
Consensus CDS Project CCDS21811.1
International Mouse Phenotyping Consortium Status Dctn5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022642 VEGA Gene Model | MGI Sequence Detail 16004 C57BL/6J ±  kb
transcript OTTMUST00000054251 VEGA | MGI Sequence Detail 1532 Not Applicable 
polypeptide OTTMUSP00000025873 VEGA | MGI Sequence Detail 182 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(2) UniProt(4)
Polymorphisms
SNPs within 2kb(169 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001451 Hexapeptide repeat
InterPro IPR011004 Trimeric LpxA-like
Protein Ontology PR:000006327 dynactin subunit 5
References
(Earliest) J:64913 Eckley DM, et al., Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the arp1 minifilament pointed end. J Cell Biol. 1999 Oct 18;147(2):307-20
(Latest) J:222159 Li Y, et al., Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Nature. 2015 May 28;521(7553):520-4
All references(41)
Other
accession IDs
MGI:1914078, MGI:2142326, MGI:5313699

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory