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Galnt6 Gene Detail
Summary
  • Symbol
    Galnt6
  • Name
    UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6
  • Synonyms
    GalNAc-T6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891640
    NCBI Gene: 207839
  • Gene Overview
    MyGene.info: GALNT6
Location & Maps
more
  • Sequence Map
    Chr15:100691813-100729376 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      37564 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 56.39 cM, cytoband F3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    GALNT6, polypeptide N-acetylgalactosaminyltransferase 6
  • Vertebrate Orthologs
    11
  • Human Ortholog
    GALNT6, polypeptide N-acetylgalactosaminyltransferase 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GalNAcT6, GALNAC-T6
  • Links
    NCBI Gene ID: 11226
    neXtProt AC: NX_Q8NCL4

  • Chr Location
    12q13; chr12:51351870-51391955 (-)  GRCh38.p2
  • HomoloGene
    Vertebrate Homology Class 5218
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;2 frog, western clawed
  • HCOP
    human homology predictions: GALNT6
  • Gene Tree
    Galnt6
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    26 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    1
  • Gene trapped
    4
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    3 involving Galnt6
  • Incidental Mutations
    Mutagenetix , APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    104
  • Tissues
    97
  • cDNA Data
    28
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035000 VEGA Gene Model | MGI Sequence Detail 37564 C57BL/6J ±  kb
transcript OTTMUST00000089005 VEGA | MGI Sequence Detail 3796 Not Applicable  
polypeptide OTTMUSP00000048580 VEGA | MGI Sequence Detail 622 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    490 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000007828 polypeptide N-acetylgalactosaminyltransferase 6
  • EC
    2.4.1.41
  • InterPro Domains
    IPR001173 Glycosyltransferase 2-like
    IPR029044 Nucleotide-diphospho-sugar transferases
    IPR000772 Ricin B, lectin domain
Molecular
Reagents
less
  • All nucleic 28
    cDNA 28

    Microarray probesets 6
Other
Accession IDs
less
MGI:2146177
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 3
    Phenotypes 26
  • Earliest
    J:64930 Bennett EP, et al., Cloning and characterization of a close homologue of human UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase-T3, designated GalNAc-T6. Evidence for genetic but not functional redundancy. J Biol Chem. 1999 Sep 3;274(36):25362-70
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/13/2016
MGI 6.05 		The Jackson Laboratory