About   Help   FAQ
Slc36a2 Gene Detail
Summary
  • Symbol
    Slc36a2
  • Name
    solute carrier family 36 (proton/amino acid symporter), member 2
  • Synonyms
    A530067G19Rik, PAT2, Tramd1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891430
    NCBI Gene: 246049
Location & Maps
more
  • Sequence Map
    Chr11:55158470-55185077 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      26608 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    SLC36A2, solute carrier family 36 (proton/amino acid symporter), member 2
  • Vertebrate Orthologs
    6
  • Human Ortholog
    SLC36A2, solute carrier family 36 (proton/amino acid symporter), member 2
    Orthology source: HomoloGene
  • Synonyms
    PAT2, TRAMD1
  • Links
    NCBI Gene ID: 153201
    neXtProt AC: NX_Q495M3

  • Chr Location
    5q33.1; chr5:151314978-151347590 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    2 with human SLC36A2 associations

Human Disease Mouse Models
       Hyperglycinuria   OMIM: 138500
Iminoglycinuria   OMIM: 242600
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Slc36a2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005685 VEGA Gene Model | MGI Sequence Detail 26608 C57BL/6J ±  kb
transcript OTTMUST00000012651 VEGA | MGI Sequence Detail 2429 Not Applicable  
polypeptide OTTMUSP00000005860 VEGA | MGI Sequence Detail 478 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    124 from dbSNP Build 137
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000015111 proton-coupled amino acid transporter 2
  • InterPro Domains
    IPR013057 Amino acid transporter, transmembrane domain
Molecular
Reagents
less
  • All nucleic 28
    cDNA 27
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2443560
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:78797 Boll M, et al., Functional characterization of two novel mammalian electrogenic proton-dependent amino acid cotransporters. J Biol Chem. 2002 Jun 21;277(25):22966-73
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory