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BY367451
Gene Detail
Symbol

Name
ID
BY367451
cDNA sequence, BY367451
MGI:1891412
Synonyms
Atxn8os, Klhl1as, Sca8
Feature Type
unclassified non-coding RNA gene
Genetic Map
Chromosome 14
Syntenic
Sequence Map
Chr14:96556570-96557009 bp
From MGI annotation of GRCm38

  440 bp   ±  kb flank

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Mouse Genome Browser
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
 
Mice both homozygous and heterozygous for disruption of this gene develop abnormalities in gait and defects in motor coordination with time. Dendritic atrophy of Purkinje cells is also seen.
 
Gene Ontology
(GO)
classifications
All GO classifications: (1 annotations)
Component cytoplasm
Other database
links
Entrez Gene108639
DFCITC1668151
DoTSDT.101357266
Sequences
Representative SequencesLengthStrain/SpeciesFlank
transcript TC1668151 DFCI | MGI Sequence Detail 450 Not Applicable 

For the selected sequences
All sequences(3)
Polymorphisms
SNPs within 2kb(32 from dbSNP Build 137)
References
(Earliest) J:62929 Nemes JP, et al., The SCA8 transcript is an antisense RNA to a brain-specific transcript encoding a novel actin-binding protein (KLHL1). Hum Mol Genet. 2000 Jun 12;9(10):1543-51
(Latest) J:112937 He Y, et al., Targeted deletion of a single Sca8 ataxia locus allele in mice causes abnormal gait, progressive loss of motor coordination, and Purkinje cell dendritic deficits. J Neurosci. 2006 Sep 27;26(39):9975-82
All references(9)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory