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Mov10l1
Gene Detail
Symbol

Name
ID
Mov10l1
Moloney leukemia virus 10-like 1
MGI:1891384
Synonyms
CHAMP, Csm
Feature Type
protein coding gene
Genetic Map
Chromosome 15
44.49 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:88982909-89055148 bp, + strand
From VEGA annotation of GRCm38

  72240 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56835  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: MOV10L1
Gene Tree: Mov10l1

Human
homologs
MOV10L1, Mov10 RISC complex RNA helicase like 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 54456
neXtProt AC: NX_Q9BXT6

Human Synonyms: CHAMP, DJ402G11.8

Human Chr (Location): 22q13.33; chr22:50090006-50161705 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(1) Radiation induced(1) Targeted(7)
Genomic Mutations involving Mov10l1 (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a targeted allele lacking the helicase domain exhibit male infertility due to meiotic arrest, apoptosis, and derepression of retrotransposons in male germ cells.
 
Phenotype Images(2)
Interactions
Mov10l1 interacts with 94 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cell proliferation, multicellular organismal development, ...
Component cytoplasm
Function ATP binding, helicase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (61)    Tissues (30)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 10
RNA in situ 14
Northern blot 36
RT-PCR 1
cDNA source data(19)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase mov10l1    NEW 
Molecular
reagents
All nucleic(23) cDNA(19) Primer pair(2) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000024857 (Evidence)
Ensembl Gene Model ENSMUSG00000015365 (Evidence)
Entrez Gene 83456 (Evidence)
UniGene 358791
DFCI TC1585453
DoTS DT.525704, DT.60100515
NIA Mouse Gene Index U016548
EC 3.6.4.13
Consensus CDS Project CCDS27737.1
International Mouse Phenotyping Consortium Status Mov10l1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024857 VEGA Gene Model | MGI Sequence Detail 72240 C57BL/6J ±  kb
transcript OTTMUST00000061245 VEGA | MGI Sequence Detail 4133 Not Applicable 
polypeptide OTTMUSP00000029997 VEGA | MGI Sequence Detail 1239 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(10) UniProt(5)
Polymorphisms
SNPs within 2kb(208 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000031109 helicase Mov10l1
References
(Earliest) J:68614 Wang PJ, et al., An abundance of X-linked genes expressed in spermatogonia. Nat Genet. 2001 Apr;27(4):422-6
(Latest) J:222128 Yu Q, et al., Type I interferon controls propagation of long interspersed element-1. J Biol Chem. 2015 Apr 17;290(16):10191-9
All references(42)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory