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Capn12 Gene Detail
Summary
  • Symbol
    Capn12
  • Name
    calpain 12
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891369
    NCBI Gene: 60594
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:28881450-28893585 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 16.94 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    242 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891369
protein coding gene Chr7:28881422-28893585 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031966
protein coding gene Chr7:27759833-27771356 (+)
A/J MGP_AJ_G0031944
protein coding gene Chr7:27038488-27050426 (+)
AKR/J MGP_AKRJ_G0031876
protein coding gene Chr7:27736409-27747944 (+)
BALB/cJ MGP_BALBcJ_G0031951
protein coding gene Chr7:27191366-27203010 (+)
C3H/HeJ MGP_C3HHeJ_G0031670
protein coding gene Chr7:28137998-28150421 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032415
protein coding gene Chr7:28638558-28650124 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029467
protein coding gene Chr7:28095912-28108081 (+)
CAST/EiJ MGP_CASTEiJ_G0031005
protein coding gene Chr7:21432265-21443861 (+)
CBA/J MGP_CBAJ_G0031636
protein coding gene Chr7:29961825-29973588 (+)
DBA/2J MGP_DBA2J_G0031788
protein coding gene Chr7:26784217-26795697 (+)
FVB/NJ MGP_FVBNJ_G0031745
protein coding gene Chr7:26872347-26884374 (+)
LP/J MGP_LPJ_G0031868
protein coding gene Chr7:28056793-28068225 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031781
protein coding gene Chr7:29384205-29397736 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032445
protein coding gene Chr7:27218405-27230005 (+)
PWK/PhJ MGP_PWKPhJ_G0030730
protein coding gene Chr7:21820398-21832457 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030563
protein coding gene Chr7:18232229-18243998 (+)
WSB/EiJ MGP_WSBEiJ_G0031114
protein coding gene Chr7:27595901-27610142 (+)



Homology
more
  • Human Ortholog
    CAPN12, calpain 12
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CAPN12, calpain 12
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 147968
    neXtProt AC: NX_Q6ZSI9
    UniProt: Q6ZSI9

  • Chr Location
    19q13.2; chr19:38730124-38744474 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 60594 NCBI Gene Model | MGI Sequence Detail 12136 C57BL/6J ±  kb
transcript NM_001110807 RefSeq | MGI Sequence Detail 2828 Not Specified  
polypeptide Q9ER56 UniProt | EBI | MGI Sequence Detail 720 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 4
    Primer pair 2

    Microarray probesets 1
References
more
  • Summaries
    All 21
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:64480 Dear TN, et al., Gene structure, chromosomal localization, and expression pattern of capn12, a new member of the calpain large subunit gene family. Genomics. 2000 Sep 1;68(2):152-60
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory