Psg23 MGI Mouse Gene Detail - MGI:1891355 - pregnancy-specific beta-1-glycoprotein 23

Symbol

Psg23
Name

pregnancy-specific beta-1-glycoprotein 23
Synonyms

1620401C02Rik

Feature Type

protein coding gene
IDs

MGI:1891355
NCBI Gene: 56868
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr7:18340268-18350426 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, 9.18 cM
Mapping Data

2 experiments

SNPs within 2kb

161 from dbSNP Build 142
Strain Annotations

9
PCR

1

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1891355	protein coding gene	Chr7:18340268-18350426 (-)
129S1/SvImJ	no annotation
A/J	MGP_AJ_G0031716	protein coding gene	Chr7:16190559-16199976 (-)
AKR/J	MGP_AKRJ_G0031641	protein coding gene	Chr7:16530432-16731456 (-)
BALB/cJ	no annotation
C3H/HeJ	MGP_C3HHeJ_G0031445	protein coding gene	Chr7:16780096-16839691 (-)
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	MGP_CBAJ_G0031406	protein coding gene	Chr7:17898306-17957928 (-)
DBA/2J	MGP_DBA2J_G0031564	protein coding gene	Chr7:16073278-16083247 (-)
FVB/NJ	MGP_FVBNJ_G0031512	protein coding gene	Chr7:15741879-16182835 (-)
LP/J	MGP_LPJ_G0031643	protein coding gene	Chr7:16720551-16765593 (-)
NOD/ShiLtJ	no annotation
NZO/HlLtJ	MGP_NZOHlLtJ_G0032215	protein coding gene	Chr7:16174701-16504540 (-)
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Human Ortholog

CEACAM7, CEA cell adhesion molecule 7

Vertebrate Orthologs

21

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CEACAM7, CEA cell adhesion molecule 7
Synonyms

CGM2
Links

HGNC:1819

NCBI Gene ID: 1087

neXtProt AC: NX_Q14002

UniProt: Q14002
Chr Location

19q13.2; chr19:41673303-41706976 (-) GRCh38

MGI Vertebrate Homology

Psg23 stringent orthology
1 human;1 mouse;2 rat;18 zebrafish
HCOP

vertebrate homology predictions: CEACAM7
Gene Tree

Psg23

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
2 phenotype references

All Mutations and Alleles

3
Endonuclease-mediated

2
Spontaneous

1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

34 strains or lines available

Mice homozygous for this spontaneous mutation display no phenotypic abnormalities.

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All GO Annotations

9
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

96
Literature Summary

2

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

19
RefSeq

2
UniProt

2
CCDS

CCDS20874.1

Ensembl

ENSMUSG00000074359 (Evidence)
NCBI Gene

56868

			Length	Strain/Species	Flank
genomic	56868	NCBI Gene Model \| MGI Sequence Detail	10159	C57BL/6J	± kb
transcript	NM_020261	RefSeq \| MGI Sequence Detail	2179	ZRU/MplStud
polypeptide	NP_064657	RefSeq \| MGI Sequence Detail	471	ZRU/MplStud

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UniProt

2 Sequences
InterPro Domains

IPR007110 Immunoglobulin-like domain

IPR036179 Immunoglobulin-like domain superfamily

IPR013783 Immunoglobulin-like fold

IPR003599 Immunoglobulin subtype

IPR003598 Immunoglobulin subtype 2

IPR013106 Immunoglobulin V-set domain

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All nucleic 97

cDNA 96

Primer pair 1

Microarray probesets 2

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MGI:1924821

Summaries

All 21

Developmental Gene Expression 2

Gene Ontology 5

Phenotypes 2
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:311151 Nakano T, et al., Effects of Ppargamma1 deletion on late-stage murine embryogenesis and cells that undergo endocycle. Dev Biol. 2021 Oct;478:222-235

TSS for Psg23:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr70840	Chr7:18350423-18350432 (-)	-2 bp
Tssr70839	Chr7:18350317-18350328 (-)	103 bp
Tssr2096	Chr7:18340963-18340982 (-)	9,453 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23