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Psg22 Gene Detail
Summary
  • Symbol
    Psg22
  • Name
    pregnancy-specific beta-1-glycoprotein 22
  • Synonyms
    cea9
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891354
    NCBI Gene: 243862
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:18452015-18461173 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 9.26 cM, cytoband A2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    226 from dbSNP Build 142
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891354
 protein coding gene Chr7:18451976-18461363 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031743
 protein coding gene Chr7:16623797-16637853 (+)
A/J no annotation
AKR/J MGP_AKRJ_G0031645
 protein coding gene Chr7:16761679-16781963 (+)
BALB/cJ MGP_BALBcJ_G0031723
 protein coding gene Chr7:16526991-16538347 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0032189
 protein coding gene Chr7:17511008-17522871 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0031408
 protein coding gene Chr7:18103003-18126337 (+)
DBA/2J MGP_DBA2J_G0031563
 protein coding gene Chr7:16073190-16083241 (-)
FVB/NJ MGP_FVBNJ_G0031514
 protein coding gene Chr7:16119011-16204597 (-)
LP/J MGP_LPJ_G0031646
 protein coding gene Chr7:17065848-17071452 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031550
 protein coding gene Chr7:17968898-17983427 (+)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CEACAM4, CEA cell adhesion molecule 4
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CEACAM4, CEA cell adhesion molecule 4
  • Synonyms
    CGM7, CGM7_HUMAN, NCA
  • Links
    NCBI Gene ID: 1089
    neXtProt AC: NX_O75871
    UniProt: O75871

  • Chr Location
    19q13.2; chr19:41613436-41627074 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    12
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044903 Ensembl Gene Model | MGI Sequence Detail 9159 C57BL/6J ±  kb
transcript ENSMUST00000108481 Ensembl | MGI Sequence Detail 1871 Not Applicable  
polypeptide ENSMUSP00000104121 Ensembl | MGI Sequence Detail 514 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 1
Other
Accession IDs
less
MGI:2141816, MGI:2681855
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 3
  • Earliest
    J:107211 Wynne F, et al., Mouse pregnancy-specific glycoproteins: tissue-specific expression and evidence of association with maternal vasculature. Reproduction. 2006 Apr;131(4):721-32
  • Latest
    J:311151 Nakano T, et al., Effects of Ppargamma1 deletion on late-stage murine embryogenesis and cells that undergo endocycle. Dev Biol. 2021 Oct;478:222-235
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory