Spock2
Gene Detail

Symbol Name ID

Spock2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2 MGI:1891351

Synonyms

Gcap26, mKIAA0275, testican-2

Feature Type

protein coding gene

Genetic Map

Chromosome 10

29.69 cM, cytoband B3
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr10:60106219-60135198 bp, + strand From VEGA annotation of GRCm38   28980 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:8854  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Spock2

Human homologs

Human Homolog		SPOCK2, sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
NCBI Gene ID		9806
neXtProt AC		NX_Q92563
Human Synonyms		testican-2
Human Chr (Location)		10pter-q25.3; chr10:73818792-73848790 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(1) Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	extracellular matrix organization, peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan, ...
Component	extracellular region, proteinaceous extracellular matrix
Function	calcium ion binding, extracellular matrix binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (2)    Tissues (2)    Images (1)
Theiler Stages: 24

Assay Type	Results
RNA in situ	2

cDNA source data(127)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(127) cDNA(127)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000029785 (Evidence)
Ensembl Gene Model	ENSMUSG00000058297 (Evidence)
Entrez Gene	94214 (Evidence)
UniGene	153429
DFCI	TC1578016, TC1608379
DoTS	DT.55277238, DT.99853998
NIA Mouse Gene Index	U011554
Consensus CDS Project	CCDS35910.1
International Mouse Knockout Project Status	Spock2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000029785	VEGA Gene Model | MGI Sequence Detail	28980	C57BL/6J
transcript	OTTMUST00000073921	VEGA | MGI Sequence Detail	5238	Not Applicable
polypeptide	OTTMUSP00000038323	VEGA | MGI Sequence Detail	423	Not Applicable

All sequences(34) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(21 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR011992	EF-hand-like domain
InterPro	IPR011497	Kazal-type serine protease inhibitor domain
InterPro	IPR002350	Proteinase inhibitor I1, Kazal
InterPro	IPR019577	SPARC/Testican, calcium-binding domain
InterPro	IPR000716	Thyroglobulin type-1
Protein Ontology	PR:000015555	testican-2

References

(Earliest) J:19885 Kambouris M, et al., Novel cDNA clones obtained by antibody screening of a mouse cerebellar cDNA expression library. Brain Res Mol Brain Res. 1994 Sep;25(3-4):183-91
(Latest) J:139122 Manabe R, et al., Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54
All references(36)

Other accession IDs

MGD-MRK-18679, MGI:101855, MGI:2143457