Fgf20
Gene Detail

Symbol Name ID

Fgf20 fibroblast growth factor 20 MGI:1891346

Feature Type

protein coding gene

Genetic Map

Chromosome 8

23.89 cM, cytoband B1.2
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr8:40279166-40308331 bp, - strand From VEGA annotation of GRCm38   29166 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:10527  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 2 zebrafish

Protein SuperFamily: fibroblast growth factor
Gene Tree: Fgf20

Human homologs

Human Homolog		FGF20, fibroblast growth factor 20
NCBI Gene ID		26281
neXtProt AC		NX_Q9NP95
Human Synonyms		FGF-20
Human Chr (Location)		8p22; chr8:16850334-16859674 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(1) : Targeted(1)
 

Mice homozygous for a knock-out allele exhibit imapired coclear lateral compartment differentiation and deafness without loss of vestibular function.

 
Phenotype Images(3)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	cell differentiation, fibroblast growth factor receptor signaling pathway, ...
Component	extracellular region
Function	fibroblast growth factor receptor binding, growth factor activity

External Resources: FuncBase

Expression

Literature Summary: (23 records)
Data Summary: Results (163)    Tissues (144)    Images (29)
Theiler Stages: 16, 17, 19, 20, 21, 22, 23, 24, 25, 28

Assay Type	Results
RNA in situ	162
RT-PCR	1

cDNA source data(9)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(12) cDNA(9) Primer pair(2) Other(1)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000031718 (Evidence)
Ensembl Gene Model	ENSMUSG00000031603 (Evidence)
Entrez Gene	80857 (Evidence)
UniGene	425526
DFCI	TC1591690
DoTS	DT.91327160
NIA Mouse Gene Index	U029749
Consensus CDS Project	CCDS52544.1
International Mouse Knockout Project Status	Fgf20

Sequences

Length	Strain/Species
genomic	OTTMUSG00000031718	VEGA Gene Model | MGI Sequence Detail	29166	C57BL/6J
transcript	OTTMUST00000078562	VEGA | MGI Sequence Detail	1476	Not Applicable
polypeptide	OTTMUSP00000041787	VEGA | MGI Sequence Detail	211	Not Applicable

All sequences(23) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(26 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR008996	Cytokine, IL-1-like
InterPro	IPR002209	Heparin-binding growth factor/Fibroblast growth factor
InterPro	IPR002348	Interleukin 1/heparin-binding growth factor
Protein Ontology	PR:000007490	fibroblast growth factor 20

References

(Earliest) J:76230 Hajihosseini MK, et al., Expression patterns of fibroblast growth factors-18 and -20 in mouse embryos is suggestive of novel roles in calvarial and limb development. Mech Dev. 2002 Apr;113(1):79-83
(Latest) J:193958 Huh SH, et al., Fgf20 governs formation of primary and secondary dermal condensations in developing hair follicles. Genes Dev. 2013 Feb 15;27(4):450-8
All references(46)