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Fgf20
Gene Detail
 Symbol
Name
ID
Fgf20
fibroblast growth factor 20
MGI:1891346
Feature Type protein coding gene
Genetic Map
Chromosome 8
23.89 cM, cytoband B1.2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:40279166-40308331 bp, - strand
From VEGA annotation of GRCm38

  29166 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10527  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: fibroblast growth factor
Gene Tree: Fgf20

Human
homologs
Human Homolog FGF20, fibroblast growth factor 20
NCBI Gene ID 26281
neXtProt AC  NX_Q9NP95
Human Synonyms  FGF-20, RHDA2
Human Chr (Location)  8p22; chr8:16992825-17002165 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human FGF20
Alleles
and
phenotypes
All alleles(1) : Targeted(1)
 
Mice homozygous for a knock-out allele exhibit imapired coclear lateral compartment differentiation and deafness without loss of vestibular function.
 
Phenotype Images(3)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cell differentiation, fibroblast growth factor receptor signaling pathway, ...
Component extracellular region
Function fibroblast growth factor receptor binding, growth factor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (26 records)
Data Summary: Results (223)    Tissues (197)    Images (33)
Theiler Stages: 16, 17, 19, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
RNA in situ 211
RT-PCR 12
cDNA source data(9)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(13) cDNA(9) Primer pair(3) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000031718 (Evidence)
Ensembl Gene ModelENSMUSG00000031603 (Evidence)
Entrez Gene80857 (Evidence)
UniGene425526
DFCITC1591690
DoTSDT.91327160
NIA Mouse Gene IndexU029749
Consensus CDS ProjectCCDS52544.1
International Mouse Knockout Project StatusFgf20
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031718 VEGA Gene Model | MGI Sequence Detail 29166 C57BL/6J ±  kb
transcript OTTMUST00000078562 VEGA | MGI Sequence Detail 1476 Not Applicable 
polypeptide OTTMUSP00000041787 VEGA | MGI Sequence Detail 211 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(311 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008996 Cytokine, IL-1-like
InterPro IPR002209 Heparin-binding growth factor/Fibroblast growth factor
Protein Ontology PR:000007490 fibroblast growth factor 20
References (Earliest) J:76230 Hajihosseini MK, et al., Expression patterns of fibroblast growth factors-18 and -20 in mouse embryos is suggestive of novel roles in calvarial and limb development. Mech Dev. 2002 Apr;113(1):79-83
(Latest) J:204446 Tateya T, et al., Hedgehog signaling regulates prosensory cell properties during the basal-to-apical wave of hair cell differentiation in the mammalian cochlea. Development. 2013 Sep;140(18):3848-57
All references(51)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory