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Prkag3
Gene Detail
 Symbol
Name
ID
Prkag3
protein kinase, AMP-activated, gamma 3 non-catatlytic subunit
MGI:1891343
Synonyms AMPKg3, AMPKg3L, AMPKg3S
Feature Type protein coding gene
Genetic Map
Chromosome 1
38.54 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr1:74739499-74749221 bp, - strand
From VEGA annotation of GRCm38

  9723 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23006  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: AMP-activated protein kinase, gamma-type regulatory subunit
Gene Tree: Prkag3

Human
homologs
Human Homolog PRKAG3, protein kinase, AMP-activated, gamma 3 non-catalytic subunit
NCBI Gene ID 53632
neXtProt AC  NX_Q9UGI9
Human Synonyms  AMPKG3
Human Chr (Location)  2q35; chr2:218822383-218831789 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human PRKAG3
Alleles
and
phenotypes
All alleles(2) : Targeted(2)
 
Homozygous null mice display impaired glycogen synthesis after exercise.
 
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process fatty acid biosynthetic process, fatty acid metabolic process, ...
Component AMP-activated protein kinase complex, extracellular space
Function adenyl nucleotide binding, AMP-activated protein kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (22)    Tissues (17)   
Theiler Stages: 13, 17, 19, 20, 21, 24, 26, 28
Assay TypeResults
Immunohistochemistry 13
RNA in situ 1
RT-PCR 8
cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(6) cDNA(4) Primer pair(1) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000034607 (Evidence)
Ensembl Gene ModelENSMUSG00000006542 (Evidence)
Entrez Gene241113 (Evidence)
DFCITC1588409, TC1693087
DoTSDT.101341463, DT.40165965, DT.55185903
NIA Mouse Gene IndexU021483
Consensus CDS ProjectCCDS15055.1, CCDS35620.1
International Mouse Knockout Project StatusPrkag3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034607 VEGA Gene Model | MGI Sequence Detail 9723 C57BL/6J ±  kb
transcript OTTMUST00000087810 VEGA | MGI Sequence Detail 2255 Not Applicable 
polypeptide OTTMUSP00000047819 VEGA | MGI Sequence Detail 489 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(7) UniProt(3)
Polymorphisms SNPs within 2kb(77 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000644 Cystathionine beta-synthase, core
Protein Ontology PR:000013227 5'-AMP-activated protein kinase subunit gamma-3
References (Earliest) J:62193 Milan D, et al., A mutation in PRKAG3 associated with excess glycogen content in pig skeletal muscle. Science. 2000 May 19;288(5469):1248-51
(Latest) J:186631 Pinter K, et al., Embryonic expression of AMPK gamma subunits and the identification of a novel gamma2 transcript variant in adult heart. J Mol Cell Cardiol. 2012 Sep;53(3):342-9
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory