Scel
Gene Detail

Symbol Name ID

Scel sciellin MGI:1891228

Synonyms

9230114I02Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 14

52.51 cM, cytoband E
Detailed Genetic Map ± 1 cM


Mapping data(5)

Sequence Map

Chr14:103513341-103613346 bp, + strand From NCBI annotation of GRCm38   100006 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:2850  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Scel

Human homologs

Human Homolog		SCEL, sciellin
NCBI Gene ID		8796
neXtProt AC		NX_O95171
Human Chr (Location)		13q22; chr13:78109809-78219398 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(1) : Targeted(1)
 

Homozygous null mice are viable and fertile with normal hair morphology and development and normal skin morphology and barrier function.

 

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	embryo development, epidermis development, ...
Component	cytoplasm, membrane, ...
Function	metal ion binding, zinc ion binding

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (42)    Tissues (34)    Images (11)
Theiler Stages: 10, 18, 23, 25, 28

Assay Type	Results
Immunohistochemistry	5
RNA in situ	32
Northern blot	4
Western blot	1

cDNA source data(22)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(22) cDNA(22)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000022123 (Evidence)
Entrez Gene	64929 (Evidence)
UniGene	244003
DFCI	TC1585799, TC1642515, TC1643521
DoTS	DT.101153028, DT.40170772
NIA Mouse Gene Index	U015934
Consensus CDS Project	CCDS37002.1
International Mouse Knockout Project Status	Scel

Sequences

Length	Strain/Species
genomic	64929	NCBI Gene Model | MGI Sequence Detail	100006	C57BL/6J
transcript	NM_022886	RefSeq | MGI Sequence Detail	3053	C57BL/6
polypeptide	Q9EQG3	UniProt | EBI | MGI Sequence Detail	652	Not Applicable

All sequences(26) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(754 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001781	Zinc finger, LIM-type
Protein Ontology	PR:000014499	sciellin

Graphical View of Protein Domain Structure

References

(Earliest) J:66221 Champliaud MF, et al., Gene characterization of sciellin (SCEL) and protein localization in vertebrate epithelia displaying barrier properties. Genomics. 2000 Dec 1;70(2):264-8
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(30)

Other accession IDs

MGI:1925008