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Chst2
Gene Detail
Symbol

Name
ID
Chst2
carbohydrate sulfotransferase 2
MGI:1891160
Synonyms
C130041E03Rik, Gn6st, GST-2, N-acetylglucosamine-6-O-sulfotransferase
Feature Type
protein coding gene
Genetic Map
Chromosome 9
50.11 cM, cytoband E3.2-3.3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:95399292-95406722 bp, - strand
From VEGA annotation of GRCm38

  7431 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3150  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Protein SuperFamily: carbohydrate sulfotransferase
Gene Tree: Chst2

Human
homologs
Human Homolog CHST2, carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
NCBI Gene ID 9435
neXtProt AC  NX_Q9Y4C5
Human Synonyms  C6ST, glcNAc6ST-1, Gn6ST-1, GST2, GST-2, HEL-S-75
Human Chr (Location)  3q24; chr3:143119776-143124014 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
 
Mice homozygous for a knock-out allele display decreased lymphocyte binding to peripheral lymph node high endothelial venules, and significantly reduced lymphocyte homing to Peyer's patches, peripheral and mesenteric lymph nodes.
 
Interactions
Chst2 interacts with 384 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (9 records)
Data Summary: Results (308)    Tissues (190)    Images (61)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 279
Northern blot 27
RT-PCR 2
cDNA source data(19)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(23) cDNA(19) Primer pair(3) Other(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000046997 (Evidence)
Ensembl Gene ModelENSMUSG00000033350 (Evidence)
Entrez Gene54371 (Evidence)
DFCITC1624874, TC1645548, TC1631134, TC1582210
DoTSDT.101376416, DT.91336761, DT.60100560, DT.91289123
NIA Mouse Gene IndexU031196, U031197
EC2.8.2.-
Consensus CDS ProjectCCDS52888.1
International Mouse Knockout Project StatusChst2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000046997 VEGA Gene Model | MGI Sequence Detail 7431 C57BL/6J ±  kb
transcript OTTMUST00000121754 VEGA | MGI Sequence Detail 7328 Not Applicable 
polypeptide OTTMUSP00000066993 VEGA | MGI Sequence Detail 530 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(95 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016469 Carbohydrate sulfotransferase
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR000863 Sulfotransferase domain
Protein Ontology PR:000005475 carbohydrate sulfotransferase 2
References
(Earliest) J:49573 Uchimura K, et al., Molecular cloning and characterization of an N-acetylglucosamine-6-O-sulfotransferase. J Biol Chem. 1998 Aug 28;273(35):22577-83
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(49)
Other
accession IDs
MGI:2143044, MGI:2143292, MGI:2444728

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory