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Chst2
Gene Detail
Symbol

Name
ID
Chst2
carbohydrate sulfotransferase 2
MGI:1891160
Synonyms
C130041E03Rik, Gn6st, GST-2, N-acetylglucosamine-6-O-sulfotransferase
Feature Type
protein coding gene
Genetic Map
Chromosome 9
50.11 cM, cytoband E3.2-3.3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:95399292-95406722 bp, - strand
From VEGA annotation of GRCm38

  7431 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3150  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: CHST2
Protein SuperFamily: carbohydrate sulfotransferase
Gene Tree: Chst2

Human
homologs
CHST2, carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 9435
neXtProt AC: NX_Q9Y4C5

Human Synonyms: C6ST, glcNAc6ST-1, Gn6ST-1, GST2, GST-2, HEL-S-75

Human Chr (Location): 3q24; chr3:143119776-143124014 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
 
Mice homozygous for a knock-out allele display decreased lymphocyte binding to peripheral lymph node high endothelial venules, and significantly reduced lymphocyte homing to Peyer's patches, peripheral and mesenteric lymph nodes.
 
Interactions
Chst2 interacts with 384 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (9 records)
Data Summary: Results (308)    Tissues (190)    Images (61)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 279
Northern blot 27
RT-PCR 2
cDNA source data(19)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase chst2 ; ZFIN chst2b    NEW 
Molecular
reagents
All nucleic(23) cDNA(19) Primer pair(3) Other(1)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000046997 (Evidence)
Ensembl Gene Model ENSMUSG00000033350 (Evidence)
Entrez Gene 54371 (Evidence)
DFCI TC1645548, TC1624874, TC1582210, TC1631134
DoTS DT.101376416, DT.60100560, DT.91336761, DT.91289123
NIA Mouse Gene Index U031196, U031197
EC 2.8.2.-
Consensus CDS Project CCDS52888.1
International Mouse Phenotyping Consortium Status Chst2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000046997 VEGA Gene Model | MGI Sequence Detail 7431 C57BL/6J ±  kb
transcript OTTMUST00000121754 VEGA | MGI Sequence Detail 7328 Not Applicable 
polypeptide OTTMUSP00000066993 VEGA | MGI Sequence Detail 530 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(95 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016469 Carbohydrate sulfotransferase
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR000863 Sulfotransferase domain
Protein Ontology PR:000005475 carbohydrate sulfotransferase 2
References
(Earliest) J:49573 Uchimura K, et al., Molecular cloning and characterization of an N-acetylglucosamine-6-O-sulfotransferase. J Biol Chem. 1998 Aug 28;273(35):22577-83
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(47)
Other
accession IDs
MGI:2143044, MGI:2143292, MGI:2444728

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory