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Aqp9
Gene Detail
Symbol

Name
ID
Aqp9
aquaporin 9
MGI:1891066
Synonyms
1700020I22Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 9
39.85 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:71110659-71168682 bp, - strand
From VEGA annotation of GRCm38

  58024 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41405  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Protein SuperFamily: aquaporin
Gene Tree: Aqp9

Human
homologs
Human Homolog AQP9, aquaporin 9
NCBI Gene ID 366
neXtProt AC  NX_O43315
Human Synonyms  AQP-9, HsT17287, SSC1
Human Chr (Location)  15q; chr15:58138209-58185911 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele have increased glycerol and triglyceride levels, increased resistance to glycerol-induced lysis, decreased glycerol permeability, and decreased susceptibility to the early stages of parasitic infection.
 
Interactions
Aqp9 interacts with 206 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (34 annotations)
Process amine transport, canalicular bile acid transport, ...
Component basolateral plasma membrane, integral component of membrane, ...
Function glycerol channel activity, porin activity, ...
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (69)    Tissues (64)    Images (8)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 7
RNA in situ 49
RT-PCR 13
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(10) Primer pair(3)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000023895 (Evidence)
Ensembl Gene ModelENSMUSG00000032204 (Evidence)
Entrez Gene64008 (Evidence)
DFCITC1574930, TC1666072, TC1679670, TC1716319
DoTSDT.101342324, DT.101368434, DT.532892, DT.91336452, DT.94302599
NIA Mouse Gene IndexU149101
Consensus CDS ProjectCCDS23325.1, CCDS72270.1
International Mouse Knockout Project StatusAqp9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023895 VEGA Gene Model | MGI Sequence Detail 58024 C57BL/6J ±  kb
transcript OTTMUST00000058379 VEGA | MGI Sequence Detail 2643 Not Applicable 
polypeptide OTTMUSP00000028277 VEGA | MGI Sequence Detail 321 Not Applicable 

For the selected sequences
All sequences(71) RefSeq(15) UniProt(5)
Polymorphisms
SNPs within 2kb(404 from dbSNP Build 137)    SNPs within 2kb including multiple locations(410)
Protein-related
information
ResourceIDDescription
InterPro IPR015685 Aquaporin 9
InterPro IPR023271 Aquaporin-like
InterPro IPR000425 Major intrinsic protein
InterPro IPR022357 Major intrinsic protein, conserved site
Protein Ontology PR:000004189 aquaporin-9
References
(Earliest) J:63371 Edashige K, et al., Expression of mRNAs of the aquaporin family in mouse oocytes and embryos. Cryobiology. 2000 Mar;40(2):171-5
(Latest) J:193645 Jelen S, et al., Aquaporin-9 and urea transporter-A gene deletions affect urea transmembrane passage in murine hepatocytes. Am J Physiol Gastrointest Liver Physiol. 2012 Dec 1;303(11):G1279-87
All references(50)
Other
accession IDs
MGI:1919512, MGI:2143005

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory