About   Help   FAQ
Aqp9
Gene Detail
Symbol

Name
ID
Aqp9
aquaporin 9
MGI:1891066
Synonyms
1700020I22Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 9
39.85 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:71110659-71168682 bp, - strand
From VEGA annotation of GRCm38

  58024 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41405  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: AQP9
Protein SuperFamily: aquaporin
Gene Tree: Aqp9

Human
homologs
AQP9, aquaporin 9
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 366
neXtProt AC: NX_O43315

Human Synonyms: AQP-9, HsT17287, SSC1

Human Chr (Location): 15q; chr15:58138209-58185911 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele have increased glycerol and triglyceride levels, increased resistance to glycerol-induced lysis, decreased glycerol permeability, and decreased susceptibility to the early stages of parasitic infection.
 
Interactions
Aqp9 interacts with 206 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (36 annotations)
Process amine transport, canalicular bile acid transport, ...
Component basolateral plasma membrane, cell, ...
Function glycerol channel activity, purine nucleobase transmembrane transporter activity, ...
External Resources: FuncBase
Expression
Literature Summary: (10 records)
Data Summary: Results (69)    Tissues (64)    Images (8)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 7
RNA in situ 49
RT-PCR 13
cDNA source data(9)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase aqp9    NEW 
Molecular
reagents
All nucleic(13) cDNA(10) Primer pair(3)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000023895 (Evidence)
Ensembl Gene Model ENSMUSG00000032204 (Evidence)
Entrez Gene 64008 (Evidence)
DFCI TC1574930, TC1716319, TC1666072, TC1679670
DoTS DT.91336452, DT.94302599, DT.532892, DT.101342324, DT.101368434
NIA Mouse Gene Index U149101
Consensus CDS Project CCDS23325.1, CCDS72270.1
International Mouse Phenotyping Consortium Status Aqp9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023895 VEGA Gene Model | MGI Sequence Detail 58024 C57BL/6J ±  kb
transcript OTTMUST00000058379 VEGA | MGI Sequence Detail 2643 Not Applicable 
polypeptide OTTMUSP00000028277 VEGA | MGI Sequence Detail 321 Not Applicable 

For the selected sequences
All sequences(71) RefSeq(15) UniProt(5)
Polymorphisms
SNPs within 2kb(404 from dbSNP Build 137)    SNPs within 2kb including multiple locations(410)
Protein-related
information
ResourceIDDescription
InterPro IPR015685 Aquaporin 9
InterPro IPR023271 Aquaporin-like
InterPro IPR000425 Major intrinsic protein
InterPro IPR022357 Major intrinsic protein, conserved site
Protein Ontology PR:000004189 aquaporin-9
References
(Earliest) J:63371 Edashige K, et al., Expression of mRNAs of the aquaporin family in mouse oocytes and embryos. Cryobiology. 2000 Mar;40(2):171-5
(Latest) J:216308 Ruan YC, et al., CFTR interacts with ZO-1 to regulate tight junction assembly and epithelial differentiation through the ZONAB pathway. J Cell Sci. 2014 Oct 15;127(Pt 20):4396-408
All references(50)
Other
accession IDs
MGI:1919512, MGI:2143005

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/23/2015
MGI 5.22
The Jackson Laboratory