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Sox16 Gene Detail
Summary
  • Symbol
    Sox16
  • Name
    SRY (sex determining region Y)-box 16
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890761
    NCBI Gene: 116912
  • Alliance
Location &
Maps
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  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 11, Syntenic
  • Mapping Data
    1 experiment
Homology
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  • Human Ortholog
    SOX15, SRY-box transcription factor 15
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SOX15, SRY-box transcription factor 15
  • Synonyms
    SOX20, SOX26, SOX27
  • Links
    NCBI Gene ID: 6665
    neXtProt AC: NX_O60248
    UniProt: O60248

  • Chr Location
    17p13.1; chr17:7588180-7590170 (-)  GRCh38.p7

Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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  • Other Mouse Links
Sequences &
Gene Models
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  • All Sequences
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
transcript L29084 GenBank | ENA | DDBJ | MGI Sequence Detail 172 Not Specified  
polypeptide Q62247 UniProt | EBI | MGI Sequence Detail 57 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR009071 High mobility group box domain
    IPR036910 High mobility group box domain superfamily
    IPR031269 Protein SOX-15
References
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  • Summaries
    All 7
    Gene Ontology 2
  • Earliest
    J:57450 Miyashita A, et al., Five different genes, Eif4a1, Cd68, Supl15h, Sox15 and Fxr2h, are clustered in a 40 kb region of mouse chromosome 11. Gene. 1999 Sep 3;237(1):53-60
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/22/2022
MGI 6.22
The Jackson Laboratory