About   Help   FAQ
Trim39 Gene Detail
Summary
  • Symbol
    Trim39
  • Name
    tripartite motif-containing 39
  • Synonyms
    1100001D15Rik, E130103K13Rik, RBCC-B30.2, RING-B box-coiled-coil-B30.2, Rnf23, tfp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890659
    NCBI Gene: 79263
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:36569764-36582896 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 19.01 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890659
 protein coding gene Chr17:36569764-36583139 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023673
 protein coding gene Chr17:36613125-36626478 (-)
A/J MGP_AJ_G0023630
 protein coding gene Chr17:35407063-35420835 (-)
AKR/J MGP_AKRJ_G0023601
 protein coding gene Chr17:35823119-35836491 (-)
BALB/cJ MGP_BALBcJ_G0023637
 protein coding gene Chr17:35602089-35616799 (-)
C3H/HeJ MGP_C3HHeJ_G0023399
 protein coding gene Chr17:36327140-36340508 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024075
 protein coding gene Chr17:38079526-38092893 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021550
 protein coding gene Chr17:33332958-33346412 (-)
CAST/EiJ MGP_CASTEiJ_G0022888
 protein coding gene Chr17:36361055-36374412 (-)
CBA/J MGP_CBAJ_G0023377
 protein coding gene Chr17:39642709-39656084 (-)
DBA/2J MGP_DBA2J_G0023501
 protein coding gene Chr17:34764693-34778051 (-)
FVB/NJ MGP_FVBNJ_G0023474
 protein coding gene Chr17:34466441-34479836 (-)
LP/J MGP_LPJ_G0023580
 protein coding gene Chr17:37022839-37036193 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023497
 protein coding gene Chr17:38449683-38463325 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024121
 protein coding gene Chr17:36132674-36146056 (-)
PWK/PhJ MGP_PWKPhJ_G0022639
 protein coding gene Chr17:33571074-33584628 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022459
 protein coding gene Chr17:34257341-34272864 (-)
WSB/EiJ MGP_WSBEiJ_G0022957
 protein coding gene Chr17:36368229-36381643 (-)



Homology
more
  • Human Ortholog
    TRIM39, tripartite motif containing 39
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRIM39, tripartite motif containing 39
  • Synonyms
    RNF23, TFP, TRIM39B
  • Links
    NCBI Gene ID: 56658
    UniProt: Q9HCM9

  • Chr Location
    6p22.1; chr6:30326469-30343729 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    40
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    827
  • Tissues
    86
  • cDNA Data
    46
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 79263 NCBI Gene Model | MGI Sequence Detail 13133 C57BL/6J ±  kb
    transcript NM_024468 RefSeq | MGI Sequence Detail 3085 Not Specified  
    polypeptide Q9ESN2 UniProt | EBI | MGI Sequence Detail 488 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 47
      cDNA 47

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1915679, MGI:2443031
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 3
      Gene Ontology 9
      Phenotypes 10
    • Earliest
      J:67238 Orimo A, et al., Molecular cloning of testis-abundant finger Protein/Ring finger protein 23 (RNF23), a novel RING-B box-coiled coil-B30.2 protein on the class I region of the human MHC. Biochem Biophys Res Commun. 2000 Sep 16;276(1):45-51
    • Latest
      J:367686 Briere A, et al., Systematic Ocular Phenotyping of Knockout Mouse Lines Identifies Genes Associated With Age-Related Corneal Dystrophies. Invest Ophthalmol Vis Sci. 2025 May 1;66(5):7
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory