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Fignl1 Gene Detail
Summary
  • Symbol
    Fignl1
  • Name
    fidgetin-like 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890648
    NCBI Gene: 60530
Location & Maps
more
  • Sequence Map
    Chr11:11787431-11808959 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      21529 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 7.08 cM, cytoband A2
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    FIGNL1, fidgetin like 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FIGNL1, fidgetin like 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 63979
    neXtProt AC: NX_Q6PIW4

  • Chr Location
    7p12.1; chr7:50444129-50450390 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    50
  • Gene trapped
    48
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005160 VEGA Gene Model | MGI Sequence Detail 21529 C57BL/6J ±  kb
transcript OTTMUST00000011528 VEGA | MGI Sequence Detail 2961 Not Applicable  
polypeptide OTTMUSP00000005361 VEGA | MGI Sequence Detail 683 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    147 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 5
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:64964 Cox GA, et al., The mouse fidgetin gene defines a new role for AAA family proteins in mammalian development. Nat Genet. 2000 Oct;26(2):198-202
  • Latest
    J:197379 Yuan J, et al., FIGNL1-containing protein complex is required for efficient homologous recombination repair. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10640-10645

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory