About   Help   FAQ
Gabarapl2
Gene Detail
Symbol

Name
ID
Gabarapl2
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2
MGI:1890602
Synonyms
0610012F20Rik, 2900019O08Rik, GATE-16, Gef2
Feature Type
protein coding gene
Genetic Map
Chromosome 8
58.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr8:111940703-111953612 bp, + strand
From VEGA annotation of GRCm38

  12910 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68550  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: GABARAPL2
Protein SuperFamily: microtubule-associated proteins 1 light chain 3A/3B
Gene Tree: Gabarapl2

Human
homologs
GABARAPL2, GABA(A) receptor-associated protein like 2
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 11345
neXtProt AC: NX_P60520

Human Synonyms: ATG8, ATG8C, GATE16, GATE-16, GEF2, GEF-2

Human Chr (Location): 16q22.1; chr16:75566351-75577881 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(75) : Gene trapped(73) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Gabarapl2 interacts with 230 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (28 annotations)
Process autophagosome assembly, autophagy, ...
Component autophagosome, autophagosome membrane, ...
Function microtubule binding, protein binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(11)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase gabarapl2    NEW 
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000031074 (Evidence)
Ensembl Gene Model ENSMUSG00000031950 (Evidence)
Entrez Gene 93739 (Evidence)
DFCI TC1573584
DoTS DT.110876031, DT.496189, DT.91425863, DT.94363782
Consensus CDS Project CCDS40480.1
International Mouse Phenotyping Consortium Status Gabarapl2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031074 VEGA Gene Model | MGI Sequence Detail 12910 C57BL/6J ±  kb
transcript OTTMUST00000076980 VEGA | MGI Sequence Detail 1677 Not Applicable 
polypeptide OTTMUSP00000040592 VEGA | MGI Sequence Detail 117 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(111 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004241 Autophagy protein Atg8 ubiquitin-like
Protein Ontology PR:000007759 gamma-aminobutyric acid receptor-associated protein-like 2
References
(Earliest) J:63409 Kneussel M, et al., The gamma-aminobutyric acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapse. Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8594-9
(Latest) J:170318 Itoh T, et al., OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation. J Cell Biol. 2011 Mar 7;192(5):839-53
All references(40)
Other
accession IDs
MGI:1861743, MGI:1915608, MGI:1920098, MGI:2142469

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/18/2015
MGI 6.0
The Jackson Laboratory