Gabarapl2
Gene Detail

Symbol Name ID

Gabarapl2 gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2 MGI:1890602

Synonyms

0610012F20Rik, 2900019O08Rik, GATE-16, Gef2

Feature Type

protein coding gene

Genetic Map

Chromosome 8

58.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr8:111940703-111953612 bp, + strand From VEGA annotation of GRCm38   12910 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:68550  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: microtubule-associated proteins 1 light chain 3A/3B
Gene Tree: Gabarapl2

Human homologs

Human Homolog		GABARAPL2, GABA(A) receptor-associated protein-like 2
NCBI Gene ID		11345
neXtProt AC		NX_P60520
Human Synonyms		ATG8, ATG8C, GATE16, GATE-16, GEF2, GEF-2
Human Chr (Location)		16q22.1; chr16:75600249-75611779 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(74) : Targeted(1) Gene trapped(73)

Gene Ontology (GO) classifications

All GO classifications: (15 annotations)

Process	autophagy, intra-Golgi vesicle-mediated transport, ...
Component	autophagic vacuole, autophagic vacuole membrane, ...
Function	protein binding

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (1 records)
cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(11) cDNA(11)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000031074 (Evidence)
Ensembl Gene Model	ENSMUSG00000031950 (Evidence)
Entrez Gene	93739 (Evidence)
DFCI	TC1573584
DoTS	DT.110876031, DT.496189, DT.91425863, DT.94363782
Consensus CDS Project	CCDS40480.1
International Mouse Knockout Project Status	Gabarapl2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000031074	VEGA Gene Model | MGI Sequence Detail	12910	C57BL/6J
transcript	OTTMUST00000076980	VEGA | MGI Sequence Detail	1677	Not Applicable
polypeptide	OTTMUSP00000040592	VEGA | MGI Sequence Detail	117	Not Applicable

All sequences(35) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(96 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004241	Autophagy protein Atg8 ubiquitin-like
Protein Ontology	PR:000007759	gamma-aminobutyric acid receptor-associated protein-like 2

References

(Earliest) J:63409 Kneussel M, et al., The gamma-aminobutyric acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapse. Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8594-9
(Latest) J:170318 Itoh T, et al., OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation. J Cell Biol. 2011 Mar 7;192(5):839-53
All references(37)

Other accession IDs

MGI:1861743, MGI:1915608, MGI:1920098, MGI:2142469