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Srsf4
Gene Detail
Symbol

Name
ID
Srsf4
serine/arginine-rich splicing factor 4
MGI:1890577
Synonyms
5730499P16Rik, MNCb-2616, Sfrs4, SRp75
Feature Type
protein coding gene
Genetic Map
Chromosome 4
64.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:131873617-131901706 bp, + strand
From VEGA annotation of GRCm38

  28090 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:25624  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Srsf4

Human
homologs
Human Homolog SRSF4, serine/arginine-rich splicing factor 4
NCBI Gene ID 6429
neXtProt AC  NX_Q08170
Human Synonyms  SFRS4, SRP75
Human Chr (Location)  1p35.3; chr1:29147738-29182125 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(19) : Gene trapped(17) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Srsf4 interacts with 128 markers (Mir10a, Mir15a, Mir26a-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process hematopoietic progenitor cell differentiation, mRNA processing, ...
Component nucleus
Function nucleic acid binding, nucleotide binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (22)    Tissues (22)    Images (4)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 20
RT-PCR 2
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) cDNA(9) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000009577 (Evidence)
Ensembl Gene ModelENSMUSG00000028911 (Evidence)
Entrez Gene57317 (Evidence)
DFCITC1603773, TC1594820, TC1576513
NIA Mouse Gene IndexU004894
Consensus CDS ProjectCCDS51315.1
International Mouse Knockout Project StatusSrsf4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009577 VEGA Gene Model | MGI Sequence Detail 28090 C57BL/6J ±  kb
transcript OTTMUST00000021987 VEGA | MGI Sequence Detail 3100 Not Applicable 
polypeptide OTTMUSP00000010024 VEGA | MGI Sequence Detail 496 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(2) UniProt(7)
Polymorphisms
SNPs within 2kb(132 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR000504 RNA recognition motif domain
Protein Ontology PR:000014761 serine/arginine-rich splicing factor 4
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:202604 Nagamachi A, et al., Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Cancer Cell. 2013 Sep 9;24(3):305-17
All references(39)
Other
accession IDs
MGI:1913899, MGI:2140593

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory