Homozygous inactivation of this gene leads to increased lean body mass and altered adipocyte lipolysis, leptin production and susceptibility to diet-induced obesity. Increased oxygen and food consumption, impaired cold adaptation, and altered glucose and blood homeostasis have also been observed.
|Ensembl Gene Model||ENSMUSG00000030546 (Evidence)|
|Entrez Gene||103968 (Evidence)|
|DFCI||TC1586310, TC1638355, TC1615867, TC1611413|
|DoTS||DT.55252902, DT.533984, DT.91418512, DT.91366491|
|NIA Mouse Gene Index||U042825|
|Consensus CDS Project||CCDS21385.1|
|International Mouse Phenotyping Consortium Status||Plin1|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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